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Product Details
11538-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Published species
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
TUSC2 Fusion Protein Ag2118 (1-110 aa encoded by BC023976)
Conjugate
Unconjugated
Form
Liquid
Concentration
0.15 mg/mL
Storage conditions
-20°C
Product Specific Information
Immunogen sequence: MGASGSKAR GLWPFASAAG GGGSEAAGAE QALVRPRGRA VPPFVFTRRG SMFYDEDGDL AHEFYEETIV TKNGQKRAKL RRVHKNLIPQ GIVKLDHPRI HVDFPVILYE V (1-110 aa encoded by BC023976)
Target Information
TUSC2 (tumor suppressor candidate 2), also known as FUS1, LGCC or PDAP2, is a 110 amino acid protein that is expressed at high levels in kidney, pancreas, lung, heart and skeletal muscle where it is thought to function as a tumor suppressor. More specifically, TUSC2 inhibits invasive colony formation by inducing G1 cell cycle arrest and ultimately causing apoptosis, thereby preventing tumor growth. The gene encoding TUSC2 maps to human chromosome 3, which houses over 1,100 genes, including a chemokine receptor (CKR) gene cluster and a variety of human cancer-related gene loci. Key tumor suppressing genes on chromosome 3 include those that encode the apoptosis mediator RASSF1, the cell migration regulator HYAL1 and the angiogenesis suppressor SEMA3B.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: Fus-1 protein; Fusion 1 protein; lung cancer candidiate, FUS; PDGFA associated protein 2; PDGFA-associated protein 2; Tumor suppressor candidate 2; TUSC 2
Gene Aliases: C3orf11; FUS1; LGCC; PDAP2; TUSC2
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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