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TWA1 Polyclonal Antibody
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FIGURE: 1 / 3
TWA1 Antibody (600-401-FS8) in ICC/IF
Immunofluorescence Microscopy of TWA1 antibody. Tissue: rat brain tissue. Fixation: 0.5% PFA. Antigen retrieval: not required. Primary antibody: TWA1 antibody at 20 µg/mL for 1 hr at RT. Secondary antibody: Fluorescein rabbit secondary antibody at 1:10,000 for 45 min at RT. Localization: TWA1 is nuclear and cytoplasmic. Staining: TWA1 as red fluorescent signal.
Product Details
600-401-FS8
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Anti-TWA1 antibody was prepared from whole rabbit serum produced by repeated immunizations with a 17 amino acid synthetic peptide near the C-terminus of human TWA1.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.2
Contains
0.02% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
Target Information
TWA1 was identified through a two hybrid-associated protein screen with RanBPM. TWA1 is well conserved through evolution and is localized within the nucleus. It interacts with RanBP9 and comprises a protein complex with RanBPM and Muskelin. TWA1 was found to possess the LisH-CTLH motif which is detected in proteins involved in microtubule dynamics, cell migration, nucleokinesis and chromosome segregation. These functions overlap with functions suggested for the RanGTPase cycle. Recent findings suggested that there is an as yet uncovered function of the RanGTPase cycle.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: BWK-1; Bwk1 leukemia-related; GID complex subunit 8 homolog; Glucose-induced degradation protein 8 homolog; protein C20orf11; protein C20orf11 homolog; Twa1; two hybrid associated protein 1; two hybrid associated protein No. 1 with RanBPM; Two hybrid-associated protein 1 with RanBPM; unnamed protein product
Gene Aliases: 2310003C23Rik; 4833420G11Rik; AI451474; Bwk1; C20orf11; GID8; TWA1
UniProt ID: (Human) Q9NWU2, (Mouse) Q9D7M1
Entrez Gene ID: (Human) 54994, (Mouse) 76425, (Rat) 296466
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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