The antibody detects endogenous levels of total TWIST1 protein.
Basic helix-loop-helix (bHLH) transcription factors have been implicated in cell lineage determination and differentiation. The protein encoded by this gene is a bHLH transcription factor and shares similarity with another bHLH transcription factor, Dermo1. The strongest expression of this mRNA is in placental tissue, in adults, mesodermally derived tissues express this mRNA preferentially. Mutations in this gene have been found in patients with Saethre-Chotzen syndrome.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: ACS3; B-HLH DNA binding protein; bHLHa38; BPES2; BPES3; charlie chaplin; Class A basic helix-loop-helix protein 38; CRS1; H-twist; M-twist; Pluridigite; polydactyly EMS; SCS; Skam10Jus; twist basic helix-loop-helix transcription factor 1; twist gene homolog 1; twist homolog 1; TWIST homolog of drosophila; Twist-related protein 1
AA960487; ACS3; BHLHA38; BPES2; BPES3; CRS; CRS1; CSO; M-Twist; Pde; pdt; SCS; Ska10; Ska