Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
Immunogen sequence: WCRFSQMLH PIFEEASDVI KEEFPNENQV VFARVDCDQH SDIAQRYRIS KYPTLKLFRN GMMMKREYRG QRSVKALADY IRQQKSDPIQ EIRDLAEITT LDRSKRNIIG YFEQKDSDNY RVFERVANIL HDDCAFLSAF GDVSKPERYS GDNIIYKPPG HSAPDMVYLG AMTNFDVTYN WIQDKCVPLV REITFENGEE LTEEGLPFLI LFHMKEDTES LEIFQNEVAR QLISEKGTIN FLHADCDKFR HPLLHIQKTP ADCPVIAIDS FRHMYVFGDF KDVLIPGKLK QFVFDLHSGK LHREFHHGPD PTDTAPGEQA QDVASSPPES SFQKLAPSEY RYTLLRDRDE L (57-406 aa encoded by BC005374)
Mediates thiol-dependent retention in the early secretory pathway, forming mixed disulfides with substrate proteins through its conserved CRFS motif. Inhibits the calcium channel activity of ITPR1. May have a role in the control of oxidative protein folding in the endoplasmic reticulum. Required to retain ERO1L and ERO1LB in the endoplasmic reticulum.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Endoplasmic reticulum resident protein 44; endoplasmic reticulum resident protein 44 kDa; ER protein 44; OTTHUMP00000063799; protein disulfide isomerase family A, member 10; thioredoxin domain containing 4 (endoplasmic reticulum); Thioredoxin domain-containing protein 4
Gene Aliases: ERP44; KIAA0573; PDIA10; TXNDC4; UNQ532/PRO1075
UniProt ID: (Human) Q9BS26
Entrez Gene ID: (Human) 23071
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