Recommended positive controls: 293T, ZBTB32 transfected 293T lysate.
Predicted reactivity: Chimpanzee (97%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
DNA-binding protein that binds to the to a 5'-TGTACAGTGT-3' core sequence. May function as a transcriptional transactivator and transcriptional repressor. Probably exerts its repressor effect by preventing GATA3 from binding to DNA. May play a role in regulating the differentiation and activation of helper T-cells. [UniProt]
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
Protein Aliases: FANCC-interacting protein; Fanconi anemia zinc finger protein; OTTHUMP00000045790; repressor of GATA; Testis zinc finger protein; Zinc finger and BTB domain-containing protein 32; Zinc finger protein 538
Gene Aliases: FAXF; FAZF; Rog; TZFP; ZBTB32; ZNF538
UniProt ID: (Human) Q9Y2Y4
Entrez Gene ID: (Human) 27033
Molecular Function: C2H2 zinc finger transcription factor