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Proteintech
Talin-1 Polyclonal Antibody
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
14168-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Published species
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Talin-1 Fusion Protein Ag5367 (2193-2541 aa encoded by BC042923)
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
0.43 mg/mL
Amount
64.5 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: GNSCRQEDV IATANLSRRA IADMLRACKE AAYHPEVAPD VRLRALHYGR ECANGYLELL DHVLLTLQKP SPELKQQLTG HSKRVAGSVT ELIQAAEAMK GTEWVDPEDP TVIAENELLG AAAAIEAAAK KLEQLKPRAK PKEADESLNF EEQILEAAKS IAAATSALVK AASAAQRELV AQGKVGAIPA NALDDGQWSQ GLISAARMVA AATNNLCEAA NAAVQGHASQ EKLISSAKQV AASTAQLLVA CKVKADQDSE AMKRLQAAGN AVKRASDNLV KAAQKAAAFE EQENETVVVK EKMVGGIAQI IAAQEEMLRK ERELEEARKK LAQIRQQQYK FLPSELRDEH (2193-2541 aa encoded by BC042923)
Target Information
Talin, a multifunctional constituent of cell-substratum attachment sites, is a high molecular weight protein (225-235 kDa) found in variety of tissues and cell types. It is localized at a subset of adherens junctions, specialized cell-cell and cell-matrix associations that are characterized by the presence of filamentous actin at the cytoplasmic face of the junctional complex. In cultured cells, talin is absent from cell-cell junctions and found predominantly at adhesion plaques and in fibrillar streaks underlying cell surface fibronectin. Talin interacts with at least two other proteins that are localized at adhesion plaques, vinculin and integrin.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: cytoskeletal protein; unnamed protein product
Gene Aliases: ILWEQ; talin-1; TLN
UniProt ID: (Human) Q9Y490, (Mouse) P26039
Entrez Gene ID: (Human) 7094, (Rat) 313494, (Mouse) 21894
cell-substrate junction assembly
cell adhesion
integrin-mediated signaling pathway
biological_process
actin cytoskeleton organization
cortical actin cytoskeleton organization
integrin activation
cell junction assembly
cortical microtubule organization
cell-cell adhesion
cell-cell junction assembly
regulation of focal adhesion assembly
platelet aggregation
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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