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Proteintech
Talin-1 Polyclonal Antibody
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Product Details
14168-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Published species
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Talin-1 Fusion Protein Ag5367 (2193-2541 aa encoded by BC042923)
Conjugate
Form
Liquid
Concentration
0.43 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: GNSCRQEDV IATANLSRRA IADMLRACKE AAYHPEVAPD VRLRALHYGR ECANGYLELL DHVLLTLQKP SPELKQQLTG HSKRVAGSVT ELIQAAEAMK GTEWVDPEDP TVIAENELLG AAAAIEAAAK KLEQLKPRAK PKEADESLNF EEQILEAAKS IAAATSALVK AASAAQRELV AQGKVGAIPA NALDDGQWSQ GLISAARMVA AATNNLCEAA NAAVQGHASQ EKLISSAKQV AASTAQLLVA CKVKADQDSE AMKRLQAAGN AVKRASDNLV KAAQKAAAFE EQENETVVVK EKMVGGIAQI IAAQEEMLRK ERELEEARKK LAQIRQQQYK FLPSELRDEH (2193-2541 aa encoded by BC042923)
Target Information
Talin, a multifunctional constituent of cell-substratum attachment sites, is a high molecular weight protein (225-235 kDa) found in variety of tissues and cell types. It is localized at a subset of adherens junctions, specialized cell-cell and cell-matrix associations that are characterized by the presence of filamentous actin at the cytoplasmic face of the junctional complex. In cultured cells, talin is absent from cell-cell junctions and found predominantly at adhesion plaques and in fibrillar streaks underlying cell surface fibronectin. Talin interacts with at least two other proteins that are localized at adhesion plaques, vinculin and integrin.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: Talin-1
Gene Aliases: ILWEQ; KIAA1027; TLN; TLN1
UniProt ID: (Human) Q9NZQ2, (Mouse) P26039
Entrez Gene ID: (Human) 7094, (Rat) 313494, (Mouse) 21894
cytoskeletal anchoring at plasma membrane
cell-substrate junction assembly
biological_process
cortical actin cytoskeleton organization
platelet aggregation
cell adhesion
platelet degranulation
movement of cell or subcellular component
muscle contraction
cell-cell junction assembly
viral process
IRE1-mediated unfolded protein response
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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