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Product Details
PA5-54076
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human Tara. Recombinant protein control fragment (Product #RP-91541).
Conjugate
Form
Liquid
Concentration
0.2 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2648222
Product Specific Information
Immunogen sequence: ATDSRTPEVP AGEGPRRGLG APLTEDQQNR LSEEIEKKWQ ELEKLPLREN KRVPLTALLN QSRGERRGPP SDGHEALEKE VQALRAQLEA WRLQGEAPQS A
Highest antigen sequence identity to the following orthologs: Mouse - 83%, Rat - 85%.
Target Information
This gene encodes a protein with an N-terminal pleckstrin homology domain and a C-terminal coiled-coil region. The protein interacts with trio, which is involved with neural tissue development and controlling actin cytoskeleton organization, cell motility and cell growth. The protein also associates with F-actin and stabilizes F-actin structures. Mutations in this gene have been associated with a form of autosomal recessive nonsyndromic deafness. Multiple alternatively spliced transcript variants that would encode different isoforms have been found for this gene, however some transcripts may be subject to nonsense-mediated decay (NMD).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Protein Tara; tara-like protein; TRF1-associated protein of 68 kDa; TRIO and F-actin-binding protein; Trio-associated repeat on actin
Gene Aliases: AI428493; DFNB28; dJ37E16.4; EST478828; HRIHFB2122; KIAA1662; mKIAA1662; TAP68; TARA; TRIOBP
UniProt ID: (Human) Q9H2D6, (Mouse) Q99KW3
Entrez Gene ID: (Human) 11078, (Rat) 362956, (Mouse) 110253
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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