This target displays homology in the following species: Cow: 92%; Dog: 92%; Guinea Pig: 83%; Horse: 85%; Human: 100%; Mouse: 100%; Rabbit: 85%; Rat: 100%
The protein encoded by this gene contains a ubiquitin-like domain in the N-terminal region, three transmembrane segments and a C-terminal 3-oxo-5-alpha steroid 4-dehydrogenase domain. The protein belongs to the steroid 5-alpha reductase family. Mutations in this gene result in ventricular tachycardia, catecholaminergic polymorphic, 3.
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Protein Aliases: steroid 5 alpha-reductase 2-like 2; Steroid 5-alpha-reductase 2-like 2 protein; synaptic glycoprotein SC2-like; Trans-2,3-enoyl-CoA reductase-like
Gene Aliases: D330017N19Rik; Srd5a2l2; Tecrl
UniProt ID: (Mouse) Q8BFZ1
Entrez Gene ID: (Mouse) 243078