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Invitrogen
Tenascin R Polyclonal Antibody
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Product Details
PA5-50580
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Synthetic peptide corresponding to a region derived from internal residues of human tenascin R
Conjugate
Form
Liquid
Concentration
2.2 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.4, with 40% glycerol
Contains
0.05% sodium azide
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
The antibody detects endogenous levels of total Tenascin R protein.
Target Information
Tenascin-R (TNR) is an extracellular matix protein expressed primarily in the central nervous system. It is a member of the tenascin (TN) gene family, which includes at least 3 genes in mammals: TNC (or hexabrachion; MIM 187380), TNX (TNXB; MIM 600985), and TNR (Erickson, 1993). The genes are expressed in distinct tissues at different times during embryonic development and are present in adult tissues.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Janusin; Neural recognition molecule J1-160/180; Restrictin; tenascin R (restrictin, janusin); Tenascin-R; Tenascin-R (Restrictin janusin J1-160/180); Tenascin-R (Restrictin, janusin, J1-160/180); TN-R
Gene Aliases: J1-tenascin; J1NRM; janusin; restrictin; TN-R; TNR
UniProt ID: (Human) Q92752, (Mouse) Q8BYI9, (Rat) Q05546
Entrez Gene ID: (Human) 7143, (Mouse) 21960, (Rat) 25567
cell adhesion
neuron cell-cell adhesion
axon guidance
associative learning
telencephalon cell migration
negative regulation of cell-cell adhesion
extracellular matrix organization
locomotory exploration behavior
negative regulation of axon extension involved in regeneration
negative regulation of synaptic transmission
synapse organization
neuromuscular process controlling balance
positive regulation of synaptic transmission, glutamatergic
positive regulation of transmission of nerve impulse
long-term synaptic potentiation
negative regulation of cell adhesion
negative regulation of neuron projection development
negative regulation of axon extension
modulation of synaptic transmission
nervous system development
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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