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          Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.

          • Primary Antibodies ›
          • TET3 Antibodies

          Active Motif

          Tet3 Polyclonal Antibody

          2 References
          View all (16) TET3 antibodies

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          Cite Tet3 Polyclonal Antibody

          • Antibody Testing Data (1)
          Tet3 Antibody in Western Blot (WB)
          Group 53 Created with Sketch.
          Tet3 Antibody in Western Blot (WB)
          Group 53 Created with Sketch.

          FIGURE: 1 / 1

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          Tet3 Antibody (61395) in WB

          Tet3 antibody (pAb) tested by Western blot. The blot was probed with Tet3 antibody at a dilution of 1:5,000. Lane 1: 293T cells transfected with Tet3. Lane 2: Mouse lung. Lane 3: Mouse muscle. Lane 4: Mouse ovary. Lane 5: Mouse spleen. Lane 6: Mouse testes. Lane 7: Mouse thymus. Lane 8: 293T cells transfected with Tet1. Lane 9: 293T cells transfected with Tet2. {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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          Tet3 Antibody in Western Blot (WB)
          Tet3 Polyclonal Antibody

          Product Details

          61395

          Applications
          Tested Dilution
          Publications

          Western Blot (WB)

          1:1,000-1:5,000
          View 1 publication 1 publication

          ChIP-sequencing (ChIP-Seq)

          -
          View 1 publication 1 publication
          Product Specifications

          Species Reactivity

          Mouse

          Published species

          Human, Mouse

          Host/Isotype

          Rabbit / IgG

          Class

          Polyclonal

          Type

          Antibody

          Immunogen

          This antibody was raised against a recombinant protein corresponding to amino acids 1159-1329 of mouse Tet3.
          View immunogen

          Conjugate

          Unconjugated Unconjugated Unconjugated

          Form

          Liquid

          Concentration

          Conc. Not Determined

          Storage buffer

          whole serum with 30% glycerol

          Contains

          0.035% sodium azide

          Storage conditions

          -20°C, Avoid Freeze/Thaw Cycles

          Shipping conditions

          Ambient (domestic); Wet ice (international)

          RRID

          AB_2793618

          Target Information

          TET3, a member of the ten-eleven-translocation (TET) family of genes, is a methylcytosine dioxygenase that catalyzes the conversion of methylcytosine to 5-hydroxymethylcytosine and is most abundantly expressed in hematopoietic cells. Unlike the related TET2 protein, mutations in TET3 have not been observed in any myeloid malignancies. TET3 has been shown to be involved in the demethylation of zygotic DNA before the first mitosis and has been suggested to be involved in the epigenetic reprogramming of the zygotic paternal DNA following natural fertilization and may also contribute to somatic cell nuclear reprogramming during animal cloning.

          For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

          Bioinformatics

          Protein Aliases: Methylcytosine dioxygenase TET3; MGC22014; probable methylcytosine dioxygenase TET3; Tet methylcytosine deoxygenase 3 isoform; tet oncogene family member 3

          View more View less

          Gene Aliases: B430006D22Rik; BC037432; D230004J03Rik; Tet3

          View more View less

          UniProt ID: (Mouse) Q8BG87

          View more View less

          Entrez Gene ID: (Mouse) 194388

          View more View less

          Function(s)
          DNA binding protein binding oxidoreductase activity metal ion binding dioxygenase activity methylcytosine dioxygenase activity
          Process(es)
          protein O-linked glycosylation multicellular organism development chromatin modification DNA demethylation of male pronucleus positive regulation of transcription from RNA polymerase II promoter oxidation-reduction process DNA demethylation histone H3-K4 trimethylation
          It has to be done as per old AB suggested Products section.
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          If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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