|ELISA (ELISA)||Assay Dependent|
|Immunoelectrophoresis (IE)||Assay Dependent|
|Tested Species reactivity||Human|
|Host / Isotype||Sheep / IgG|
|Immunogen||Thrombin (active site blocked) from bovine prothrombin.|
|Storage buffer||0.01M HEPES, pH 7.4, with 0.15M NaCl, 50% glycerol|
|Storage conditions||-20° C, Avoid Freeze/Thaw Cycles|
PA1-74124 detects Thrombin from human samples. Reacts weakly with mouse, pig, and rat.
PA1-74124 has been successfully used in ELISA and immunoelectrophoresis applications.
The PA1-74124 immunogen is Thrombin (active site blocked) from bovine prothrombin.
Coagulation factor II is proteolytically cleaved to form thrombin in the first step of the coagulation cascade which ultimately results in the stemming of blood loss. F2 also plays a role in maintaining vascular integrity during development and postnatal life. Mutations in F2 leads to various forms of thrombosis and dysprothrombinemia.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: prepro-coagulation factor II; prothrombin; prothrombin B-chain; serine protease
Gene Aliases: PT; RPRGL2; THPH1
UniProt ID: (Human) P00734
Entrez Gene ID: (Human) 2147
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