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Fabgennix
Timeless Polyclonal Antibody
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
TMLS-101AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Synthetic peptide:SGTPRVHRKKRFQIEDEDDcoresponding to amino acids 1178-1197 on Mouse Timeless protein.
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
0.5-1.5 mg/mL
Purification
Affinity chromatography
Storage buffer
proprietary buffer, pH 7.4-7.8, with 0.5% BSA, 30% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
Target Information
The general transcription factor IIE (TFIIE) is part of the RNA polymerase II transcription initiation complex, recruiting TFIIH and being essential for promoter clearance by RNA polymerase II. TFIIE is a heterodimer (and sometimes heterotetramer) of alpha and beta subunits. The protein encoded by this gene represents the beta subunit of TFIIE.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: mTIM; timeless; timeless circadian clock; timeless homolog; timeless-like protein; unnamed protein product
Gene Aliases: Debt69; rTIM; rTLP; Tim
UniProt ID: (Mouse) Q9R1X4, (Rat) Q9Z2Y1
Entrez Gene ID: (Mouse) 21853, (Rat) 83508
DNA replication checkpoint
negative regulation of transcription from RNA polymerase II promoter
branching involved in ureteric bud morphogenesis
kidney development
morphogenesis of an epithelium
DNA repair
cellular response to DNA damage stimulus
circadian rhythm
lung development
replication fork processing
intra-S DNA damage checkpoint
regulation of circadian rhythm
positive regulation of circadian rhythm
replication fork arrest
cell cycle phase transition
negative regulation of transcription, DNA-templated
branching morphogenesis of an epithelial tube
cellular response to hydroxyurea
cellular response to cisplatin
cellular response to bleomycin
positive regulation of double-strand break repair via homologous recombination
positive regulation of double-strand break repair
regulation of cell proliferation
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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