This Antibody was verified by Relative expression to ensure that the antibody binds to the antigen stated.
Immunogen sequence: GTVSTSCYLA VQVSEEFEKE TTAVTEKFTT EEKRFVESRD VVMTDTSLTE EQAGPGEPAA PYFITKPVVQ KLVEGGSVVF GCQVGGNPKP HVYWKKSGVP LTTGYRYKVS YNKQTGECKL VISMTFADDA GEYT
Highest antigen sequence identity to the following orthologs: Mouse - 93%, Rat - 27%.
Monoclonal Anti-Titin can be used for study of the elastic filaments within sarcomeric structures. It is also useful as a differentiation marker in the separation of rhabdomyosarcomas from other muscle tumors. By indirect immunofluorescence the antibody displays a typical striated staining pattern on frozen sections of chicken skeletal and cardiac muscle tissues. Stains the region of the A-I junction by indirect immunofluorescence. It shows a decoration line 0.05 mm from the end of the A band in electron micro-graphs. In immunoblotting using total extracts of chicken breast muscle the antibody reacts specifically with both bands of the titin doublet, and showed no reaction with nebulin.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: 188.8.131.52; Connectin; DKFZp451N061; FLJ26020; FLJ26409; FLJ32040; FLJ34413; FLJ39564; FLJ43066; Rhabdomyosarcoma antigen MU-RMS-40.14; Titin
Gene Aliases: CMD1G; CMH9; CMPD4; EOMFC; HMERF; LGMD2J; MYLK5; TMD; TTN
UniProt ID: (Human) Q8WZ42
Entrez Gene ID: (Human) 7273
Molecular Function: immunoglobulin receptor superfamily