Immunogen sequence: HFLSILTIDT SDAEDYSCVL VEDENVKTTA KLIVEGAVVE FVKELQDIEV PESYSGELEC IVSPENIEGK WYHNDVELKS NGKYTITSRR GRQNLTVKDV TKEDQGEYSF VIDGKKTTCK LKMK
Monoclonal Anti-Titin can be used for study of the elastic filaments within sarcomeric structures. It is also useful as a differentiation marker in the separation of rhabdomyosarcomas from other muscle tumors. By indirect immunofluorescence the antibody displays a typical striated staining pattern on frozen sections of chicken skeletal and cardiac muscle tissues. Stains the region of the A-I junction by indirect immunofluorescence. It shows a decoration line 0.05 mm from the end of the A band in electron micro-graphs. In immunoblotting using total extracts of chicken breast muscle the antibody reacts specifically with both bands of the titin doublet, and showed no reaction with nebulin.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: CMD1G; CMH9; CMPD4; Connectin; FLJ32040; LGMD2J; MYLK5; Rhabdomyosarcoma antigen MU-RMS-40.14; Titin; TMD
Gene Aliases: CMD1G; CMH9; CMPD4; EOMFC; HMERF; LGMD2J; MYLK5; TMD; TTN
UniProt ID: (Human) Q8WZ42
Entrez Gene ID: (Human) 7273