PA5-30747 targets Tollip in IHC (P) and WB applications and shows reactivity with Human samples.
The PA5-30747 immunogen is recombinant fragment corresponding to a region within amino acids 69 and 274 of Human Tollip.
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This gene encodes a ubiquitin-binding protein that interacts with several Toll-like receptor (TLR) signaling cascade components. The encoded protein regulates inflammatory signaling and is involved in interleukin-1 receptor trafficking and in the turnover of IL1R-associated kinase.
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Protein Aliases: adapter protein; IL-1RAcPIP; Toll-interacting protein
Gene Aliases: IL-1RAcPIP; TOLLIP
UniProt ID: (Human) Q9H0E2
Entrez Gene ID: (Human) 54472