PA3-913 detects transferrin from human and mouse samples.
PA3-913 has been successfully used in Western Blot and ICC/IF procedures.
The PA3-913 immunogen is human transferrin isolated from plasma.
Transferrins (Tf) are an approximately 80kDa blood plasma glycoprotein synthesized by the liver. They are iron binding transport proteins which can bind two Fe(3+) ions in association with the binding of an anion, usually bicarbonate. It is responsible for the transport of iron from sites of absorption and heme degradation to those of storage and utilization. Transferrin is the primary blood iron transport protein and under normal conditions; approximately one-third of total blood transferrin contains bound iron. Measurement of blood transferrin levels can be used as an indicator for blood iron-carrying capacity and abnormalities of iron metabolism such as anaemia, iron overload and haemochromatosis. Serum transferrin may also have a further role in stimulating cell proliferation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Beta-1 metal-binding globulin; DKFZp781D0156; epididymis secretory sperm binding protein Li 71p; hypotransferrinemia with hemochromatosis; PRO1557; PRO2086; Serotransferrin; Siderophilin; Transferrin
Gene Aliases: AI266983; Cd176; HEL-S-71p; HP; hpx; PRO1400; PRO1557; PRO2086; TF; Tfn; TFQTL1; Trf