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Product Details
PA5-65560
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant Human Treslin. Recombinant protein control fragment (Product #RP-106233).
Conjugate
Form
Liquid
Concentration
0.5 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Wet ice
RRID
AB_2663838
Product Specific Information
Immunogen sequence: DIGVVEESPEK GDEISLRRSP RIKQLSFSRT HSASFYSVSQ PKSRSVQRVH SFQQDKSDQR ENSPVQSIRS PKSLLFGAMS EMISPSE
Highest antigen sequence identity to the following orthologs - mouse 78%, rat 82%.
Target Information
Regulator of DNA replication and S/M and G2/M checkpoints. Regulates the triggering of DNA replication initiation via its interaction with TOPBP1 by participating in CDK2-mediated loading of CDC45L onto replication origins. Required for the transition from pre-replication complex (pre-RC) to pre-initiation complex (pre-IC). Required to prevent mitotic entry after treatment with ionizing radiation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: TOPBP1-interacting checkpoint and replication regulator; topBP1-interacting replication-stimulating protein; TopBP1-interacting, replication-stimulating protein; Treslin
Gene Aliases: C15orf42; SLD3; TICRR; Treslin
UniProt ID: (Human) Q7Z2Z1
Entrez Gene ID: (Human) 90381
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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