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Invitrogen
Tryptase Polyclonal Antibody
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FIGURE: 1 / 3
Tryptase Antibody (PA5-102552) in ICC/IF
Immunofluorescent analysis of TPSAB1 in HeLa cells. Samples were fixed with paraformaldehyde, permeabilized with 0.1% Triton X-100, blocked with 10% serum (45 min at 25°C), incubated with mouse anti-beta tubulin and TPSAB1 polyclonal antibody (Product # PA5-102552) using a dilution of 1:200 (1 hr, 37°C), and followed by goat anti-rabbit IgG Alexa Fluor 594 (red) and goat anti-mouse IgG Alexa Fluor 488 (green).
Product Details
PA5-102552
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthesized peptide derived from human TPSAB1(Accession Q15661), corresponding to amino acid residues D223-K273.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.4, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Antibody detects endogenous levels of total TPSAB1.
Target Information
Tryptase is a protein that belongs to the family of serine proteases and is primarily found in mast cells. It plays a crucial role in the immune response by cleaving and activating other proteins involved in inflammation and tissue repair. Tryptase is also involved in the regulation of blood pressure and has been implicated in various diseases, including asthma, allergies, and cardiovascular disorders. Its structure consists of four identical subunits that form a tetramer, and it is activated by proteolytic cleavage of its proenzyme form.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: mast cell alpha II tryptase; mast cell beta I tryptase; Mast cell protease 7; mast cell-restricted serine protease 7; MMCP-7; rMCP-7; TPSG1/TPSB2/TPSAB1/TPSD1; Tryptase; tryptase alpha II; Tryptase alpha-1; Tryptase alpha/beta-1; tryptase beta 1; tryptase beta I; tryptase beta-1; Tryptase I; Tryptase, skin; Tryptase-1; tryptase-I; tryptase-III
Gene Aliases: Mcp-7; Mcp7; Mcpt7; MMCP-7; rMCP-7; TPS1; TPS2; TPSAB1; TPSB1
UniProt ID: (Human) Q15661, (Rat) P27435, (Mouse) Q02844
Entrez Gene ID: (Human) 7177, (Rat) 54271, (Mouse) 100503895
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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