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Invitrogen
Tryptase Polyclonal Antibody
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FIGURE: 1 / 5
Tryptase Antibody (PA5-80177) in IHC (P)
Immunohistochemistry (Paraffin) analysis of Tryptase in paraffin-embedded section of human intestinal cancer tissue using Tryptase Polyclonal Antibody (Product # PA5-80177). Heat mediated antigen retrieval was performed in EDTA buffer (pH 8.0, epitope retrieval solution). The tissue section was blocked with 10% goat serum. The tissue section was then incubated with the primary antibody at a 1 µg/mL dilution... View More
Product Details
PA5-80177
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
E. coli-derived human Mast Cell Tryptase recombinant protein (Position: H65-P275).
Conjugate
Form
Lyophilized
Concentration
500 µg/mL
Amount
100 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS with 5mg BSA
Contains
0.05mg sodium azide
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 µg/mL.
Positive Control - WB: 293T whole cell. IHC: human lung cancer tissue, human breast cancer tissue, human intestinal cancer tissue.
Target Information
Tryptase is a protein that belongs to the family of serine proteases and is primarily found in mast cells. It plays a crucial role in the immune response by cleaving and activating other proteins involved in inflammation and tissue repair. Tryptase is also involved in the regulation of blood pressure and has been implicated in various diseases, including asthma, allergies, and cardiovascular disorders. Its structure consists of four identical subunits that form a tetramer, and it is activated by proteolytic cleavage of its proenzyme form.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: alternatively spliced; alternatively spliced; serine protease; epididymis secretory sperm binding protein; mast cell alpha II tryptase; mast cell beta I tryptase; mast cell tryptase; serine protease; TPSB2; TPSG1/TPSB2/TPSAB1/TPSD1; tryptase alpha II; Tryptase alpha-1; Tryptase alpha/beta-1; tryptase beta I; tryptase beta-1; Tryptase beta-2; Tryptase I; Tryptase II; Tryptase-1; tryptase-I; tryptase-III
Gene Aliases: TPS1; TPS2; TPSAB1; TPSB1; TPSB2; Tryptase-2
UniProt ID: (Human) Q15661
Entrez Gene ID: (Human) 7177
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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