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Bethyl Laboratories
Tyro3 Polyclonal Antibody
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FIGURE: 1 / 2
Tyro3 Antibody (A300-242A) in WB
Detection of human Tyro3 by western blot and immunoprecipitation. Samples: Whole cell lysate (50 µg for A; 500 µg for B) from U937 cells. Antibody: Affinity purified rabbit anti-Tyro3 antibody BL1154 (Cat. No. A300-242A) used at the indicated concentrations for WB (A and B) and at 10 µg/mg of lysate for IP (B). Another rabbit polyclonal antibody was used in IP as a negative control (Ctrl IP). Detection: Chemiluminescence with exposure times of 5 minutes (A) and 30 minutes (B).
Product Details
A300-242A
Applications
Tested Dilution
Publications
Product Specifications
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Between 850 and C-term
Conjugate
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Storage conditions
4°C
Shipping conditions
Wet ice
Product Specific Information
The recommended shelf life for this product is 1 year from date of receipt.
Target Information
TYRO3 (tyrosine-protein kinase receptor TYRO3) is a receptor tyrosine kinase that transduces signals from the extracellular matrix into the cytoplasm by binding to several ligands including TULP1 or GAS6. It regulates many physiological processes including cell survival, migration, and differentiation. Ligand binding at the cell surface induces dimerization and autophosphorylation of TYRO3 on its intracellular domain that provides docking sites for downstream signaling molecules. Following activation by a ligand, TYRO3 plays a role in various processes such as neuron protection from excitotoxic injury, platelet aggregation, signal transduction, cell adhesion. and cytoskeleton reorganization.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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