This Antibody was verified by Relative expression to ensure that the antibody binds to the antigen stated. View Details
Immunogen sequence: MAENDVDNELL DYEDDEVETA AGGD
Highest antigen sequence identity to the following orthologs - mouse 96%, rat 96%.
This gene encodes a member of the DEAD box family of RNA-dependent ATPases that mediate ATP hydrolysis during pre-mRNA splicing. The encoded protein is an essential splicing factor required for association of U2 small nuclear ribonucleoprotein with pre-mRNA, and also plays an important role in mRNA export from the nucleus to the cytoplasm. A cluster of genes, BAT1-BAT5, is localized in the vicinity of the genes for TNF alpha and TNF beta. These genes are all within the human major histocompatibility complex class III region. Mutations in this gene may be associated with rheumatoid arthritis. Alternatively spliced transcript variants encoding the same protein have been described.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: 56 kDa U2AF65-associated protein; ATP-dependent RNA helicase p47; DEAD (Asp-Glu-Ala-Asp) box polypeptide 39B; DEAD box protein UAP56; HLA-B-associated transcript 1 protein; nuclear RNA helicase (DEAD family); spliceosome RNA helicase BAT1; Spliceosome RNA helicase DDX39B
Gene Aliases: BAT1; D6S81E; DDX39B; UAP56
UniProt ID: (Human) Q13838
Entrez Gene ID: (Human) 7919