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Proteintech
UBA2 Polyclonal Antibody
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Product Details
15347-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
UBA2 Fusion Protein Ag7586 (294-640 aa encoded by BC003153)
Conjugate
Form
Liquid
Concentration
0.13 mg/mL
Amount
19.5 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: TNASDQQNE PQLGLKDQQV LDVKSYARLF SKSIETLRVH LAEKGDGAEL IWDKDDPSAM DFVTSAANLR MHIFSMNMKS RFDIKSMAGN IIPAIATTNA VIAGLIVLEG LKILSGKIDQ CRTIFLNKQP NPRKKLLVPC ALDPPNPNCY VCASKPEVTV RLNVHKVTVL TLQDKIVKEK FAMVAPDVQI EDGKGTILIS SEEGETEANN HKKLSEFGIR NGSRLQADDF LQDYTLLINI LHSEDLGKDV EFEVVGDAPE KVGPKQAEDA AKSITNGSDD GAQPSTSTAQ EQDDVLIVDS DEEDSSNNAD VSEEERSRKR KLDEKENLSA KRSRIEQKEE LDDVIALD (294-640 aa encoded by BC003153)
Target Information
UBA2 is involved in covalent attachment of one protein to another is one of the more prominent posttranslational modifications in respect to size and ubiquity. Ubiquitin is the most familiar of the protein modifiers and its activation and transfer to target proteins has been studied extensively. Recently, a new group of ubiquitin-like proteins has been receiving a lot of attention. SUMO, or Sentrin, is one of the most intriguing. SUMO has been implicated in the stabilization of target proteins and/or their localization to sub-cellular complexes.The conjugation of SUMO-1, SUMO-2 and SUMO-3 onto target proteins requires the concerted action of the specific E1-activating enzyme SAE1/SAE2, the E2-conjugating enzyme Ubc9, and an E3-like SUMO ligase.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: Anthracycline-associated resistance ARX; FLJ13058; HRIHFB2115; similar to Saccharomyces cerevisiae UBA2; SUMO-1 activating enzyme subunit 2; SUMO-activating enzyme subunit 2; SUMO1 activating enzyme subunit 2; UBA2; UBA2, ubiquitin-activating enzyme E1 homolog; ubiquitin-like 1 (sentrin) activating enzyme E1B; ubiquitin-like 1 (sentrin) activating enzyme subunit 2; Ubiquitin-like 1-activating enzyme E1B; Ubiquitin-like modifier-activating enzyme 2; unnamed protein product
Gene Aliases: AA986091; ACCES; ARX; HRIHFB2115; SAE2; UBA1; UBA2; Ubl1a2; UBLE1B
UniProt ID: (Human) Q9UBT2, (Mouse) Q9Z1F9
Entrez Gene ID: (Human) 10054, (Mouse) 50995
nucleotide binding
magnesium ion binding
protein binding
ATP binding
small protein activating enzyme activity
transferase activity
SUMO activating enzyme activity
SUMO binding
small protein activating enzyme binding
ubiquitin-like protein conjugating enzyme binding
metal ion binding
protein heterodimerization activity
transcription factor binding
UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity
ligase activity
ribosomal S6-glutamic acid ligase activity
coenzyme F420-0 gamma-glutamyl ligase activity
coenzyme F420-2 alpha-glutamyl ligase activity
protein-glycine ligase activity
protein-glycine ligase activity, initiating
protein-glycine ligase activity, elongating
tubulin-glycine ligase activity
protein-glutamic acid ligase activity
tubulin-glutamic acid ligase activity
ubiquitin-protein ligase
Disclaimer
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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