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          Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.

          • Primary Antibodies ›
          • UBE1L2 Antibodies

          Proteintech

          UBA6 Polyclonal Antibody

          3 References
          View all (12) UBE1L2 antibodies

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          Datasheet
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          Datasheet
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          Cite UBA6 Polyclonal Antibody

          • Antibody Testing Data (7)
          UBA6 Antibody in Immunocytochemistry (ICC/IF)
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          UBA6 Antibody in Immunocytochemistry (ICC/IF)
          Group 53 Created with Sketch.

          FIGURE: 1 / 7

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          UBA6 Antibody (13211-1-AP) in ICC/IF

          Immunofluorescent analysis of ( 4% PFA ) fixed SH-SY5Y cells using 13211-1-AP (UBA6 antibody) at dilution of 1:50 and Alexa Fluor 488-conjugated AffiniPure Goat Anti-Rabbit IGG (H+L). {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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          UBA6 Antibody in Immunocytochemistry (ICC/IF)
          UBA6 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          UBA6 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          UBA6 Antibody in Western Blot (WB)
          UBA6 Antibody in Western Blot (WB)
          UBA6 Antibody in Western Blot (WB)
          UBA6 Antibody in Western Blot (WB)

          Product Details

          13211-1-AP

          Applications
          Tested Dilution
          Publications

          Western Blot (WB)

          1:500-1:1,000
          View 1 publication 1 publication

          Immunohistochemistry (IHC)

          -
          View 1 publication 1 publication

          Immunohistochemistry (Paraffin) (IHC (P))

          1:200
          -

          Immunocytochemistry (ICC/IF)

          1:50-1:500
          -

          Immunoprecipitation (IP)

          -
          View 1 publication 1 publication
          Product Specifications

          Species Reactivity

          Human, Mouse

          Published species

          Human, Mouse

          Host/Isotype

          Rabbit / IgG

          Class

          Polyclonal

          Type

          Antibody

          Immunogen

          UBA6 Fusion Protein Ag4000 (87-389 aa encoded by BC031637)
          View immunogen

          Conjugate

          Unconjugated Unconjugated Unconjugated

          Form

          Liquid

          Concentration

          0.27 mg/mL

          Purification

          Antigen affinity chromatography

          Storage buffer

          PBS, pH 7.3, with 50% glycerol

          Contains

          0.02% sodium azide

          Storage conditions

          -20°C

          Shipping conditions

          Wet ice (domestic); Dry ice (international)

          Product Specific Information

          This antibody recognizes the full-length (118 kDa) and the truncated isoform CRA_b (60-70 kDa) of UBA6 (NCBI).

          Immunogen sequence: AVTIHDTEK CQAWDLGTNF FLSEDDVVNK RNRAEAVLKH IAELNPYVHV TSSSVPFNET TDLSFLDKYQ CVVLTEMKLP LQKKINDFCR SQCPPIKFIS ADVHGIWSRL FCDFGDEFEV LDTTGEEPKE IFISNITQAN PGIVTCLENH PHKLETGQFL TFREINGMTG LNGSIQQITV ISPFSFSIGD TTELEPYLHG GIAVQVKTPK TVFFESLERQ LKHPKCLIVD FSNPEAPLEI HTAMLALDQF QEKYSRKPNV GCQQDSEELL KLATSISETL EEKVTIEIYG CPNICLLIHK CSVY (87-389 aa encoded by BC031637)

          Target Information

          UBA6 (UBE1L2, MOP-4) is a novel E1 enzyme specific for ubiquitin and belongs to the ubiquitin-activating E1 family. It is a part of the cascade to attach ubiquitin (Ub) covalently to substrate proteins. UBA6 activates ubiquitin by first adenylating its carboxy-terminal glycine residue with ATP and then linking this residue to the side chain of a cysteine residue in E1, yielding an ubiquitin-E1 thioester and free AMP. Its isoforms influence spermatogenesis and male fertility. UBA6 is highly expressed in human monocytes.

          For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

          Bioinformatics

          Protein Aliases: E1-L2; Monocyte protein 4; MOP-4; UBA6, ubiquitin-activating enzyme E1; Ubiquitin-activating enzyme 6; ubiquitin-activating enzyme E1-like 2; Ubiquitin-activating enzyme E1-like protein 2; ubiquitin-like modifier activating enzyme 6; Ubiquitin-like modifier-activating enzyme 6

          View more View less

          Gene Aliases: 4930542H01; 5730469D23Rik; AU021846; AW124799; E1-L2; MOP-4; MOP4; UBA6; UBE1L2

          View more View less

          UniProt ID: (Human) A0AVT1, (Mouse) Q8C7R4

          View more View less

          Entrez Gene ID: (Human) 55236, (Mouse) 231380

          View more View less

          Function(s)
          ubiquitin activating enzyme activity protein binding ATP binding FAT10 activating enzyme activity nucleotide binding small protein activating enzyme activity ligase activity ubiquitin-protein ligase
          Process(es)
          ubiquitin-dependent protein catabolic process learning locomotory behavior protein ubiquitination amygdala development hippocampus development protein ubiquitination involved in ubiquitin-dependent protein catabolic process dendritic spine development cellular protein modification process
          It has to be done as per old AB suggested Products section.
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          If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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