Peptide sequence: RSKTKVPVQD QVLLLGSKIL KPRRSLSSYG IDKEKTIHLT LKVVKPSDEE
Sequence homology: Cow: 86%; Horse: 86%; Human: 100%; Mouse: 86%; Pig: 86%; Rabbit: 85%; Rat: 86%
UBD qualifies as a marker for an interferon response in hepatocellular carcinoma and colon carcinoma but is not significantly overexpressed in cancers lacking a proinflammatory environment. Immunohistochemical studies demonstrated increased UBD expression in HIV-associated nephropathy and in autosomal dominant polycystic kidney disease.
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Protein Aliases: Diubiquitin; FAT10; GABBR1; UBD-3; Ubiquitin D; Ubiquitin-like protein FAT10
Gene Aliases: BOS_21713; FAT10; GABBR1; UBD; UBD-3