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UBE1 Antibody (PA5-11959) in IHC (P)
Immunohistochemistry analysis of UBE1 in formalin-fixed and paraffin-embedded human cancer tissue. Samples were incubated with UBE1 polyclonal antibody (Product # PA5-11959) which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. BC = breast carcinoma; HC = hepato... View More
Product Details
PA5-11959
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
KLH conjugated synthetic peptide between 1026-1058 amino acids from the C-terminal region of human E1 Ubiquitin (UBE1)
Conjugate
Form
Liquid
Purification
Ammonium sulfate precipitation, Size-exclusion - Dialysis
Storage buffer
PBS, pH 7.4
Contains
0.09% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2211449
Product Specific Information
This antibody is predicted to react with bovine, rat and rabbit based on sequence homology.
Target Information
UBE1 catalyzes the first step in ubiquitin conjugation to mark cellular proteins for degradation. This gene complements an X-linked mouse temperature-sensitive defect in DNA synthesis, and thus may function in DNA repair. It is part of a gene cluster on chromosome Xp11. 23. Alternative splicing results in 2 transcript variants encoding the same protein, but with different 5' UTR.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: A1S9 protein; A1S9T and BN75 temperature sensitivity complementing; POC20 centriolar protein homolog; Protein A1S9; testicular secretory protein Li 63; UBA1, ubiquitin-activating enzyme E1 homolog A; Ubiquitin-activating enzyme E1; Ubiquitin-activating enzyme E1 X; ubiquitin-activating enzyme E1, Chr X; ubiquitin-like modifier activating enzyme 1; Ubiquitin-like modifier-activating enzyme 1; Ubiquitin-like modifier-activating enzyme 1 X
Gene Aliases: A1S9; A1S9T; A1ST; AMCX1; CFAP124; GXP1; POC20; Sbx; SMAX2; UBA1; UBA1A; Ube-1; UBE1; Ube1ax; UBE1X
UniProt ID: (Human) P22314, (Mouse) Q02053
Entrez Gene ID: (Human) 7317, (Mouse) 22201
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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