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Product Details
PA5-88493
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 300-600 of human UBA1 (NP_6950121)
Conjugate
Form
Liquid
Concentration
0.57 mg/mL
Purification
Affinity Chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.01% thimerosal
Storage conditions
-20° C, Avoid Freeze/Thaw Cycles
Shipping conditions
Wet ice
RRID
AB_2804952
Product Specific Information
Immunogen sequence: KISFKSLVAS LAEPDFVVTD FAKFSRPAQL HIGFQALHQF CAQHGRPPRP RNEEDAAELV ALAQAVNARA LPAVQQNNLD EDLIRKLAYV AAGDLAPINA FIGGLAAQEV MKACSGKFMP IMQWLYFDAL ECLPEDKEVL TEDKCLQRQN RYDGQVAVFG SDLQEKLGKQ KYFLVGAGAI GCELLKNFAM IGLGCGEGGE IIVTDMDTIE KSNLNRQFLF RPWDVTKLKS DTAAAAVRQM NPHIRVTSHQ NRVGPDTERI YDDDFFQNLD GVANALDNVD ARMYMDRRCV YYRKPLLESG T; Positive Samples: U-251MG, Rat spleen; Cellular Location: Cytoplasm, Mitochondrion, Nucleus, Nucleus
Target Information
UBE1 catalyzes the first step in ubiquitin conjugation to mark cellular proteins for degradation. This gene complements an X-linked mouse temperature-sensitive defect in DNA synthesis, and thus may function in DNA repair. It is part of a gene cluster on chromosome Xp11. 23. Alternative splicing results in 2 transcript variants encoding the same protein, but with different 5' UTR.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: A1S9 protein; A1S9T and BN75 temperature sensitivity complementing; POC20 centriolar protein homolog; Protein A1S9; testicular secretory protein Li 63; uba1 {ECO:0000312|EMBL:AAH85791.1, ECO:0000312|RGD:1359327}; UBA1, ubiquitin-activating enzyme E1 homolog A; Ubiquitin-activating enzyme E1; Ubiquitin-activating enzyme E1 X; ubiquitin-activating enzyme E1 {ECO:0000250|UniProtKB:Q02053}; ubiquitin-activating enzyme E1, Chr X; ubiquitin-like modifier activating enzyme 1; Ubiquitin-like modifier-activating enzyme 1; Ubiquitin-like modifier-activating enzyme 1 X; ubiquitin-like modifier-activating enzyme 1 {ECO:0000250|UniProtKB:Q02053}
Gene Aliases: A1S9; A1S9T; A1ST; AMCX1; CFAP124; GXP1; POC20; Sbx; SMAX2; UBA1; UBA1A; Ube-1; UBE1; Ube1ax; UBE1X
UniProt ID: (Human) P22314, (Mouse) Q02053, (Rat) Q5U300
Entrez Gene ID: (Human) 7317, (Mouse) 22201, (Rat) 314432
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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