|Tested species reactivity||Mouse|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Recombinant protein fragment corresponding to a region within amino acids 1 and 102 of Human UBE2B|
|Purification||Antigen affinity chromatography|
|Storage buffer||0.1M tris glycine, pH 7, with 20% glycerol|
|Storage Conditions||-20° C, Avoid Freeze/Thaw Cycles|
|Tested Applications||Dilution *|
|Western Blot (WB)||1:500-1:3000|
PA5-30200 targets UBE2B in WB applications and shows reactivity with mouse samples.
The PA5-30200 immunogen is recombinant protein fragment corresponding to a region within amino acids 1 and 102 of Human UBE2B.
The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. This enzyme is required for post-replicative DNA damage repair. Its protein sequence is 100% identical to the mouse, rat, and rabbit homologs, which indicates that this enzyme is highly conserved in eukaryotic evolution.
E2 protein; E2-17kDa; E214K; HHR6B; HR6B; RAD6 homolog B; RAD6B; UBC2; ubiquitin carrier protein B; ubiquitin-conjugating enzyme E2 B; ubiquitin-conjugating enzyme E2-17 kDa; ubiquitin-conjugating enzyme E2B (RAD6 homolog); ubiquitin-conjugating enzyme E2B, RAD6 homology; ubiquitin-protein ligase B
2610301N02Rik; E2-14k; HR6B; mHR6B; Rad6b; Ube2b