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Invitrogen
UBE2D2 Polyclonal Antibody
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Product Details
PA5-30968
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Published species
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Full length human UBE2D2 Recombinant protein.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7, with 1% BSA, 20% glycerol
Contains
0.01% thimerosal
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Recommended positive controls: NT2D1, IMR32, U87-MG, MCF-7.
Predicted reactivity: Rat (100%), Zebrafish (98%), Xenopus laevis (92%), Pig (98%), Bovine (100%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. This enzyme functions in the ubiquitination of the tumor-suppressor protein p53, which is induced by an E3 ubiquitin-protein ligase. Two alternatively spliced transcript variants have been found for this gene and they encode distinct isoforms.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: (E3-independent) E2 ubiquitin-conjugating enzyme D2; E2 ubiquitin-conjugating enzyme D2; p53-regulated ubiquitin-conjugating enzyme 1; Ubiquitin carrier protein D2; ubiquitin conjugating enzyme E2D 2; Ubiquitin-conjugating enzyme E2 D2; Ubiquitin-conjugating enzyme E2(17)KB 2; Ubiquitin-conjugating enzyme E2-17 kDa 2; ubiquitin-conjugating enzyme E2D 2 (homologous to yeast UBC4/5); Ubiquitin-protein ligase D2
Gene Aliases: E2(17)KB2; PUBC1; UBC4; UBC4/5; UBC5B; UBCH4; UBCH5B; UBE2D2
UniProt ID: (Human) P62837
Entrez Gene ID: (Human) 7322
protein polyubiquitination
stimulatory C-type lectin receptor signaling pathway
cellular protein modification process
ubiquitin-dependent protein catabolic process
protein ubiquitination
TRIF-dependent toll-like receptor signaling pathway
Fc-epsilon receptor signaling pathway
T cell receptor signaling pathway
protein autoubiquitination
regulation of transcription from RNA polymerase II promoter in response to hypoxia
protein K48-linked ubiquitination
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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