Search
Proteintech
UBE2D3 Polyclonal Antibody
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promotions']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.viewpromo']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promocode']}}: {{promo.promoCode}} {{promo.promoTitle}} {{promo.promoDescription}}. {{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.learnmore']}}
Additional Information:
{{banner.description}}
Product Details
11677-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Published species
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
UBE2D3 Fusion Protein Ag2278 (1-147 aa encoded by BC003395)
Conjugate
Form
Liquid
Concentration
0.87 mg/mL
Amount
130.5 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: MALKRINKE LSDLARDPPA QCSAGPVGDD MFHWQATIMG PNDSPYQGGV FFLTIHFPTD YPFKPPKVAF TTRIYHPNIN SNGSICLDIL RSQWSPALTI SKVLLSICSL LCDPNPDDPL VPEIARIYKT DRDKYNRISR EWTQKYAM (1-147 aa encoded by BC003395)
Target Information
The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance. The protein encoded by this gene is an ATP-dependent drug efflux pump for xenobiotic compounds with broad substrate specificity. It is responsible for decreased drug accumulation in multidrug-resistant cells and often mediates the development of resistance to anticancer drugs. This protein also functions as a transporter in the blood-brain barrier.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: (E3-independent) E2 ubiquitin-conjugating enzyme D3; E2 ubiquitin-conjugating enzyme D3; E2(17)KB 3; MGC43926; MGC5416; PAPase; Phosphoarginine phosphatase; predicted protein of HQ2116; UBE2D3; Ubiquitin carrier protein D3; ubiquitin conjugating enzyme E2D 3; Ubiquitin-conjugating enzyme E2 D3; Ubiquitin-conjugating enzyme E2(17)KB 3; Ubiquitin-conjugating enzyme E2-17 kDa 3; ubiquitin-conjugating enzyme E2D 3 (homologous to yeast UBC4/5); ubiquitin-conjugating enzyme E2D 3 (UBC4/5 homolog, yeast); Ubiquitin-protein ligase D3; unnamed protein product
Gene Aliases: 1100001F19Rik; 9430029A22Rik; AA414951; E2(17)KB3; UBC4/5; UBC5C; UBCH5C; UBE2D3
UniProt ID: (Human) P61077, (Mouse) P61079, (Rat) P61078
Entrez Gene ID: (Human) 7323, (Mouse) 66105, (Rat) 81920
negative regulation of transcription from RNA polymerase II promoter
protein polyubiquitination
DNA repair
ubiquitin-dependent protein catabolic process
protein monoubiquitination
apoptotic process
cellular response to DNA damage stimulus
protein ubiquitination
negative regulation of BMP signaling pathway
protein modification process
proteasome-mediated ubiquitin-dependent protein catabolic process
protein autoubiquitination
protein K48-linked ubiquitination
protein K11-linked ubiquitination
protein K6-linked ubiquitination
positive regulation of protein targeting to mitochondrion
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Learn more
We're here to help
Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.
Contact tech support