Proteintech

UBE2S Polyclonal Antibody

UBE2S Antibody in Immunohistochemistry (Paraffin) (IHC (P))

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UBE2S Antibody (14115-1-AP) in IHC (P)

Immunohistochemistry of paraffin-embedded human liver cancer tissue slide using 14115-1-AP (UBE2S antibody) at dilution of 1:200 (under 40x lens) heat mediated antigen retrieved with Tris-EDTA buffer (pH 9).

UBE2S Antibody in Immunoprecipitation (IP)

Product Image Gallery

Product Details

14115-1-AP

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:3,000

View 6 publications 6 publications

Immunohistochemistry (IHC)

View 3 publications 3 publications

Immunohistochemistry (Paraffin) (IHC (P))

1:50-1:500

Flow Cytometry (Flow)

0.5 µg/1x10^6 cells

Immunoprecipitation (IP)

0.5-4.0 µg

View 1 publication 1 publication

Product Specifications

Species Reactivity

Human, Mouse, Rat

Published species

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

UBE2S Fusion Protein Ag5264 (1-222 aa encoded by BC066948)

View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.29 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Wet ice (domestic); Dry ice (international)

Product Specific Information

Immunogen sequence: MNSNVENLP PHIIRLVYKE VTTLTADPPD GIKVFPNEED LTDLQVTIEG PEGTPYAGGL FRMKLLLGKD FPASPPKGYF LTKIFHLNVG ANGEICVNVL KRDWTAELGI RHVLLTIRCL LIHPNPESAL NEEAGRLLLE NSEEYAARAR LLTEIHGGAG GPSGRAEAGR ALASGTAASS TDPGAPGGLG GAEGPMAKKH AGERDKKLAA KKKTDKKRAL RRL (1-222 aa encoded by BC066948)

Target Information

This gene encodes a member of the ubiquitin-conjugating enzyme family. The encoded protein is able to form a thiol ester linkage with ubiquitin in a ubiquitin activating enzyme-dependent manner, a characteristic property of ubiquitin carrier proteins.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Product References

BMP4 preserves the developmental potential of mESCs through Ube2s- and Chmp4b-mediated chromosomal stability safeguarding.

Protein & cell

Wang M,Zhao K,Liu M,Wang M,Qiao Z,Yi S,Jiang Y,Kou X,Zhao Y,Yin J,Li T,Wang H,Jiang C,Gao S,Chen J

Mon Aug 01 00:00:00 UTC 2022

UBE2S as a novel ubiquitinated regulator of p16 and β-catenin to promote bone metastasis of prostate cancer.

International journal of biological sciences

Peng S,Chen X,Huang C,Yang C,Situ M,Zhou Q,Ling Y,Huang H,Huang M,Zhang Y,Cheng L,Zhang Q,Guo Z,Lai Y,Huang J

Thu Jun 02 00:00:00 UTC 2022

UBE2S as a novel ubiquitinated regulator of p16 and β-catenin to promote bone metastasis of prostate cancer.

International journal of biological sciences

Peng S,Chen X,Huang C,Yang C,Situ M,Zhou Q,Ling Y,Huang H,Huang M,Zhang Y,Cheng L,Zhang Q,Guo Z,Lai Y,Huang J

Thu Jun 02 00:00:00 UTC 2022

UBE2S promotes the progression and Olaparib resistance of ovarian cancer through Wnt/β-catenin signaling pathway.

Journal of ovarian research

Hu W,Li M,Chen Y,Gu X

Fri Sep 17 00:00:00 UTC 2021

UBE2S promotes the progression and Olaparib resistance of ovarian cancer through Wnt/β-catenin signaling pathway.

Journal of ovarian research

Hu W,Li M,Chen Y,Gu X

Fri Sep 17 00:00:00 UTC 2021

The Role of CHK1 Varies with the Status of Oestrogen-receptor and Progesterone-receptor in the Targeted Therapy for Breast Cancer.

International journal of biological sciences

Xu W,Huang M,Guo J,Zhang H,Wang D,Liu T,Liu H,Chen S,Gao P,Mu K

Mon Sep 27 00:00:00 UTC 2021

Ubiquitin-Conjugating Enzyme 2S Enhances Viral Replication by Inhibiting Type I IFN Production through Recruiting USP15 to Deubiquitinate TBK1.

Cell reports

Huang L,Liu H,Zhang K,Meng Q,Hu L,Zhang Y,Xiang Z,Li J,Yang Y,Chen Y,Cui S,Tang H,Pei H,Bu Z,Weng C

Tue Aug 18 00:00:00 UTC 2020

Ubiquitin-Conjugating Enzyme 2S Enhances Viral Replication by Inhibiting Type I IFN Production through Recruiting USP15 to Deubiquitinate TBK1.

Cell reports

Huang L,Liu H,Zhang K,Meng Q,Hu L,Zhang Y,Xiang Z,Li J,Yang Y,Chen Y,Cui S,Tang H,Pei H,Bu Z,Weng C

Tue Aug 18 00:00:00 UTC 2020

UBE2S associated with OSCC proliferation by promotion of P21 degradation via the ubiquitin-proteasome system.

Biochemical and biophysical research communications

Yoshimura S,Kasamatsu A,Nakashima D,Iyoda M,Kasama H,Saito T,Takahara T,Endo-Sakamoto Y,Shiiba M,Tanzawa H,Uzawa K

Sat Apr 15 00:00:00 UTC 2017

UBE2S associated with OSCC proliferation by promotion of P21 degradation via the ubiquitin-proteasome system.

Biochemical and biophysical research communications

Yoshimura S,Kasamatsu A,Nakashima D,Iyoda M,Kasama H,Saito T,Takahara T,Endo-Sakamoto Y,Shiiba M,Tanzawa H,Uzawa K

Sat Apr 15 00:00:00 UTC 2017

UBE2S associated with OSCC proliferation by promotion of P21 degradation via the ubiquitin-proteasome system.

Biochemical and biophysical research communications

Yoshimura S,Kasamatsu A,Nakashima D,Iyoda M,Kasama H,Saito T,Takahara T,Endo-Sakamoto Y,Shiiba M,Tanzawa H,Uzawa K

Sat Apr 15 00:00:00 UTC 2017

UBE2S associated with OSCC proliferation by promotion of P21 degradation via the ubiquitin-proteasome system.

Biochemical and biophysical research communications

Yoshimura S,Kasamatsu A,Nakashima D,Iyoda M,Kasama H,Saito T,Takahara T,Endo-Sakamoto Y,Shiiba M,Tanzawa H,Uzawa K

Sat Apr 15 00:00:00 UTC 2017

Bioinformatics

Protein Aliases: E2 ubiquitin-conjugating enzyme S; E2-EPF; E2-EPF5; Ubiquitin carrier protein S; ubiquitin conjugating enzyme E2S; Ubiquitin-conjugating enzyme E2 S; ubiquitin-conjugating enzyme E2-24 kD; Ubiquitin-conjugating enzyme E2-24 kDa; Ubiquitin-conjugating enzyme E2-EPF5; ubiquitin-conjugating enzyme E2S; Ubiquitin-protein ligase S

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Gene Aliases: 0910001J09Rik; 6720465F12Rik; AA409170; E2-EPF; E2EPF; EPF5; OK/SW-cl.73; RGD1564746; UBE2S

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UniProt ID: (Human) Q16763, (Rat) B5DFI8, (Mouse) Q921J4

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Entrez Gene ID: (Human) 27338, (Rat) 292588, (Mouse) 77891

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Function(s)

ubiquitin-protein transferase activity ATP binding ubiquitin protein ligase binding ubiquitin protein ligase activity ubiquitin conjugating enzyme activity ligase activity ubiquitin-like protein transferase activity nucleotide binding ubiquitin-protein ligase

Process(es)

cellular protein modification process exit from mitosis free ubiquitin chain polymerization anaphase-promoting complex-dependent catabolic process protein K29-linked ubiquitination protein K27-linked ubiquitination cell division protein K63-linked ubiquitination protein K11-linked ubiquitination protein K6-linked ubiquitination positive regulation of ubiquitin protein ligase activity protein polyubiquitination ubiquitin-dependent protein catabolic process cell cycle

Performance Guarantee

If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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UBE2S Polyclonal Antibody

UBE2S Antibody (14115-1-AP) in IHC (P)

Product Details

14115-1-AP

Western Blot (WB)

Immunohistochemistry (IHC)

Immunohistochemistry (Paraffin) (IHC (P))

Flow Cytometry (Flow)

Immunoprecipitation (IP)

Species Reactivity

Published species

Host/Isotype

Class

Type

Immunogen

Conjugate

Form

Concentration

Purification

Storage buffer

Contains

Storage conditions

Shipping conditions

Product Specific Information

Target Information

Bioinformatics

Performance Guarantee

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