Search
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Proteintech
UBE4B Polyclonal Antibody
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promotions']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.viewpromo']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promocode']}}: {{promo.promoCode}} {{promo.promoTitle}} {{promo.promoDescription}}. {{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.learnmore']}}
Product Details
18148-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Published species
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
UBE4B Fusion Protein Ag12836 (825-1173 aa encoded by BC093696)
Conjugate
Form
Liquid
Concentration
0.25 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: EMIENHPLS TKLLVPSLMK FYTDVEHTGA TSEFYDKFTI RYHISTIFKS LWQNIAHHGT FMEEFNSGKQ FVRYINMLIN DTTFLLDESL ESLKRIHEVQ EEMKNKEQWD QLPRDQQQAR QSQLAQDERV SRSYLALATE TVDMFHILTK QVQKPFLRPE LGPRLAAMLN FNLQQLCGPK CRDLKVENPE KYGFEPKKLL DQLTDIYLQL DCARFAKAIA DDQRSYSKEL FEEVISKMRK AGIKSTIAIE KFKLLAEKVE EIVAKNARAE IDYSDAPDEF RDPLMDTLMT DPVRLPSGTI MDRSIILRHL LNSPTDPFNR QTLTESMLEP VPELKEQIQA WMREKQNSDH (825-1173 aa encoded by BC093696)
Target Information
The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. UBE4B represents an additional conjugation factor, E4, which is involved in multiubiquitin chain assembly. UBE4B also the strongest candidate among the neuroblastoma tumor suppressors.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: homologous to yeast UFD2; Homozygously deleted in neuroblastoma 1; homozygously deleted in neuroblastoma-1; RING-type E3 ubiquitin transferase E4 B; Ubiquitin conjugation factor E4 B; Ubiquitin fusion degradation protein 2; ubiquitin-fusion degradation protein 2; ubiquitination factor E4B (homologous to yeast UFD2); ubiquitination factor E4B (UFD2 homolog, yeast); ubiquitination factor E4B, UFD2 homolog; UFD2A-III/UBE4B-III splice isoform
Gene Aliases: 4930551I19Rik; 4933406G05Rik; AU014668; D4Bwg0973e; E4; HDNB1; KIAA0684; mKIAA0684; UBE4B; UBOX3; UFD2; UFD2A; Ufd2p
UniProt ID: (Human) O95155, (Mouse) Q9ES00
Entrez Gene ID: (Human) 10277, (Mouse) 63958, (Rat) 298652
protein polyubiquitination
ventricular trabecula myocardium morphogenesis
protein monoubiquitination
granzyme-mediated apoptotic signaling pathway
response to UV
neuron projection development
response to endoplasmic reticulum stress
protein ubiquitination involved in ubiquitin-dependent protein catabolic process
proteasome-mediated ubiquitin-dependent protein catabolic process
protein autoubiquitination
ubiquitin-dependent protein catabolic process
protein ubiquitination
cellular protein catabolic process
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Learn more
We're here to help
Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.
Contact tech support