Sequence of this protein is as follows: MAASQVLGEK INILSGETVK AGDRDPLGND CPEQDRLPQR SWRQKCASYV LALRPWSFSA SLTPVALGSA LAYRSHGVLD PRLLVGCAVA VLAVHGAGNL
A novel gene designated TERE1, has a significant effect on the growth regulation in bladder cancer. The TERE1 gene maps to a chromosome locus that has been identified by loss of heterozygosity studies as a site of a putative tumor suppressor gene or genes for multiple tumor types including prostate carcinoma. Data suggest that TERE1 may be significant in prostate cancer growth regulation and the down regulation or absence of TERE1 may be an important component of the phenotype of advanced disease. Data also suggest a potential role for this gene product in the progression of bladder cancer.
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Protein Aliases: RP4-796F18.1; transitional epithelia response protein; Transitional epithelial response protein 1; UbiA prenyltransferase domain-containing protein 1
Gene Aliases: 1200002M06Rik; AI426463; AW320947; RGD1309588; SCCD; TERE1; UBIAD1
Molecular Function: transferase