|Tested species reactivity||Human, Mouse, Rat|
|Host / Isotype||Rabbit / IgG|
|Immunogen||15 amino acid peptide near the carboxy terminus of human UBIAD1|
|Purification||Antigen affinity chromatography|
|Contains||0.02% sodium azide|
|Storage Conditions||Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C|
|Tested Applications||Dilution *|
|Immunofluorescence (IF)||20 µg/ml|
|Immunohistochemistry (Paraffin) (IHC (P))||5 µg/ml|
|Western Blot (WB)||1-2 µg/ml|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
A recommended positive control is mouse liver.
A ubiquitously expressed gene designated TERE1 (Transitional Epithelial Response Gene 1), which maps to chromosome 1p36.11-1p36.33, has a significant effect on growth regulation of bladder cancer and may play an equally significant role in growth regulation of prostate cancer. The TERE1 gene is located between the micro-satellite markers D1S2667 and D1S434, a chromosome locus that has been identified as a site of a tumor suppressor gene or genes for multiple tumor types. Induced TERE1 expression in two prostate carcinoma cell lines, LNCaP and PC-3, decreased proliferation up to 80% with a significant increase in the number of cells in G1. The TERE1 transcript is present in most normal human tissues, but is reduced or absent in the majority of muscle invasive TCC (Transitional Cell Carcinoma of the bladder) tumors.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.