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|Tested species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Recombinant fragment corresponding to a region within amino acids 73 and 457 of Human UBP1|
|Purification||Antigen affinity chromatography|
|Storage buffer||0.1M tris glycine, pH 7, with 10% glycerol|
|Storage Conditions||-20° C, Avoid Freeze/Thaw Cycles|
|Tested Applications||Dilution *|
|Western Blot (WB)||1:500-1:3000|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
PA5-28343 targets UBP1 in WB applications and shows reactivity with Human samples.
The PA5-28343 immunogen is recombinant fragment corresponding to a region within amino acids 73 and 457 of Human UBP1.
Functions as a transcriptional activator in a promoter context-dependent manner. Modulates the placental expression of CYP11A1. Involved in regulation of the alpha-globin gene in erythroid cells. Activation of the alpha-globin promoter in erythroid cells is via synergistic interaction with TFCP2 (By similarity). Involved in regulation of the alpha-globin gene in erythroid cells. Binds strongly to sequences around the HIV-1 initiation site and weakly over the TATA-box. Represses HIV-1 transcription by inhibiting the binding of TFIID to the TATA-box.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
LBP-1a; LBP-1B; LBP1A; LBP1B; transcription factor LBP-1; upstream-binding protein 1
LBP-1a; LBP-1B; LBP1; LBP1A; LBP1B; UBP1