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Applications | Tested Dilution | Publications |
---|---|---|
Immunohistochemistry (Paraffin) (IHC (P)) |
1:50-1:500 | - |
Product Specifications | |
---|---|
Species Reactivity |
Human |
Host/Isotype |
Rabbit / IgG |
Class |
Polyclonal |
Type |
Antibody |
Immunogen |
UCN Fusion Protein Ag15995 (1-124 aa encoded by BC104470) |
Conjugate |
Unconjugated |
Form |
Liquid |
Concentration |
0.23 mg/mL |
Purification |
Antigen affinity chromatography |
Storage buffer |
PBS, pH 7.3, with 50% glycerol |
Contains |
0.02% sodium azide |
Storage conditions |
-20°C |
Immunogen sequence: MRQAGRAAL LAALLLLVQL CPGSSQRSPE AAGVQDPSLR WSPGARNQGG GARALLLLLA ERFPRRAGPG RLGLGTAGER PRRDNPSLSI DLTFHLLRTL LELARTQSQR ERAEQNRIIF DSVGK (1-124 aa encoded by BC104470)
Urocortin (UCN), a 40 amino acids neuropeptide widely distributed in the central nervous system (CNS), belongs to a family of structurally related peptides including corticotrophin releasing factor (CRF), sauvagine and urotensin I. Urocortin is derived from a larger precursor protein (pro-urocortin, also named corticotensin). Urocortin has biological actions similar to CRF such as stress-related endocrine, autonomic and behavioral responses in mammalian species. It is a potent stimulator of adrenocorticotropic hormone (ACTH) secretion by corticotroph cells from the anterior pituitary in vitro and in vivo.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: prepro-urocortin; Urocortin; urocortin, preproprotein
Gene Aliases: UCN; UI; UROC
UniProt ID: (Human) P55089
Entrez Gene ID: (Human) 7349
Molecular Function:
peptide hormone
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