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Invitrogen
UCN2 Polyclonal Antibody
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Product Details
PA5-76952
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant full length Human UCN2.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Target Information
UCN2 (Urocortin 2) is a Protein Coding gene. Diseases associated with UCN2 include Body Mass Index Quantitative Trait Locus 11. Among its related pathways are Signaling by GPCR and Presynaptic function of Kainate receptors. Gene Ontology (GO) annotations related to this gene include signaling receptor binding and G protein-coupled receptor binding. An important paralog of this gene is UCN3. This gene is a member of the sauvagine/corticotropin-releasing factor/urotensin I family. It is structurally related to the corticotropin-releasing factor (CRF) gene and the encoded product is an endogenous ligand for CRF type 2 receptors. In the brain it may be responsible for the effects of stress on appetite. In spite of the gene family name similarity, the product of this gene has no sequence similarity to urotensin II. [provided by RefSeq, Jul 2008]
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: prepro-urocortin 2; SRP; Stresscopin-related peptide; Ucn II; urocortin 3; Urocortin II; Urocortin-2; Urocortin-related peptide
Gene Aliases: SRP; Ucn II; Ucn-2; UCN-II; UCN2; Ucn3; UCNI; UR; URP
UniProt ID: (Human) Q96RP3, (Mouse) Q99ML8
Entrez Gene ID: (Human) 90226, (Mouse) 171530, (Rat) 170896
cAMP biosynthetic process
response to stress
adenylate cyclase-activating G-protein coupled receptor signaling pathway
digestion
cell proliferation
negative regulation of gene expression
cellular response to nutrient levels
negative regulation of luteinizing hormone secretion
negative regulation of follicle-stimulating hormone secretion
response to immobilization stress
tissue regeneration
cellular response to glucocorticoid stimulus
cellular response to hypoxia
hormone-mediated signaling pathway
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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