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Product Details
PA5-69265
| Applications | Tested Dilution | Publications |
|---|---|---|
Western Blot (WB) |
1.0 µg/mL | View 1 publication 1 publication |
| Product Specifications | |
|---|---|
Species Reactivity |
Mouse |
Published species |
Rat |
Host/Isotype |
Rabbit / IgG |
Class |
Polyclonal |
Type |
Antibody |
Immunogen |
synthetic peptide corresponding to a region of mouse UCP4 |
Conjugate |
Unconjugated |
Form |
Liquid |
Concentration |
0.5 mg/mL |
Purification |
Affinity chromatography |
Storage buffer |
PBS with 2% sucrose |
Contains |
0.09% sodium azide |
Storage conditions |
-20° C, Avoid Freeze/Thaw Cycles |
RRID |
AB_2691117 |
Product Specific Information
This target displays homology in the following species: Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Sheep: 100%; Zebrafish: 85%
Target Information
UCP4 is a 323 amino acid mitochondrial uncoupling protein belonging to the large mitochondrial substrate carrier family with three Solcar repeats. UCP4 is a mitochondrial transport carrier that facilitates the transfer of anions from the inner to the outer mitochondrial membrane and the return transfer of protons from the outer to the inner mitochondrial membrane. It reduces the mitochondrial membrane potential in mammalian cells and is involved in thermoregulatory heat production. UCP4 creates proton leaks across the inner mitochondrial membrane, thus uncoupling oxidative phosphorylation from ATP synthesis resulting in dissipation of energy in the form of heat. UCP4 is usually found in adult and fetal brain, with low levels in spinal chord, corpus callosum and substantia nigra.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: mitochondrial uncoupling protein 4; uncoupling protein
Gene Aliases: 3632410G24Rik; 9430092A03Rik; D530043E16Rik; Ucp4
Entrez Gene ID: (Mouse) 74011
Molecular Function:
transporter
secondary carrier transporter
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