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Invitrogen
UGCG Polyclonal Antibody
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Product Details
PA5-42111
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Published species
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Synthetic peptide directed towards the N-terminal of human UGCG (aa 35-84).
Conjugate
Form
Liquid
Concentration
0.5 mg/mL
Amount
50 µg
Purification
Affinity Chromatography
Storage buffer
PBS with 2% sucrose
Contains
0.09% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Peptide sequence: LHLNKKATDK QPYSKLPGVS LLKPLKGVDP NLINNLETFF ELDYPKYEVL
Sequence homology: Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Yeast: 77%; Zebrafish: 100%
Target Information
May serve as a "flippase" as well as a glucosyltransferase that transfers glucose to ceramide. It Catalyzes; UDP-glucose + Nacylsphingosine = UDP + D-glucosyl-N-acylsphingosine. Ceramide Glycosyltransferase is the first step in the Glycosphingolipid synthesis; first glycosylation step. Glucosylceramide synthase (GlcT) and lactosylceramide synthase (GalT) are key enzymes for the synthesis of major glycosphingolipids of vertebrates.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: Ceramide glucosyltransferase; GCS; GLCT-1; Glucosylceramide synthase; Glycosylceramide synthase; UDP-glucose ceramide glucosyltransferase; UDP-glucose:N-acylsphingosine D-glucosyltransferase; unnamed protein product
Gene Aliases: GCS; GLCT1; UGCG
UniProt ID: (Human) Q16739
Entrez Gene ID: (Human) 7357
protein lipidation
lipid metabolic process
sphingolipid metabolic process
glucosylceramide biosynthetic process
glycosphingolipid biosynthetic process
epidermis development
regulation of signal transduction
cell differentiation
keratinocyte differentiation
leptin-mediated signaling pathway
neuron development
establishment of skin barrier
intestinal lipid absorption
cornified envelope assembly
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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