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Invitrogen
UGDH Polyclonal Antibody
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Product Details
PA5-57754
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human UGDH. Recombinant protein control fragment (Product #RP-96633).
Conjugate
Form
Liquid
Concentration
0.1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Immunogen sequence: IDMNDYQRRR FASRIIDSLF NTVTDKKIAI LGFAFKKDTG DTRESSSIYI SKYLMDEGAH LHIYDPKVPR EQIVVDLSHP GVSEDDQVSR LV
Highest antigen sequence identity to the following orthologs: Mouse - 99%, Rat - 99%.
Target Information
The protein encoded by this gene converts UDP-glucose to UDP-glucuronate and thereby participates in the biosynthesis of glycosaminoglycans such as hyaluronan, chondroitin sulfate, and heparan sulfate. These glycosylated compounds are common components of the extracellular matrix and likely play roles in signal transduction, cell migration, and cancer growth and metastasis. The expression of this gene is up-regulated by transforming growth factor beta and down-regulated by hypoxia.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: UDP UGD; UDP-Glc dehydrogenase; UDP-glucose 6-dehydrogenase; UDP-glucose dehydrogenase; uridine diphospho-glucose dehydrogenase
Gene Aliases: GDH; UDP-GlcDH; UDPGDH; UGD; UGDH
UniProt ID: (Human) O60701
Entrez Gene ID: (Human) 7358
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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