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Product Details
PA5-92155
| Applications | Tested Dilution | Publications |
|---|---|---|
Western Blot (WB) |
1:200-1:2,000 | View 1 publication 1 publication |
| Product Specifications | |
|---|---|
Species Reactivity |
Human, Mouse, Rat |
Published species |
Not Applicable |
Host/Isotype |
Rabbit / IgG |
Class |
Polyclonal |
Type |
Antibody |
Immunogen |
Recombinant fusion protein containing a sequence corresponding to amino acids 280-480 of human UGT2B4 |
Conjugate |
Unconjugated |
Form |
liquid |
Concentration |
1.84 mg/mL |
Purification |
Affinity Chromatography |
Storage buffer |
PBS, pH 7.3, with 50% glycerol |
Contains |
0.02% sodium azide |
Storage conditions |
-20° C, Avoid Freeze/Thaw Cycles |
RRID |
AB_2806395 |
Product Specific Information
Immunogen sequence: LHCKPAKPLP KEMEEFVQSS GENGVVVFSL GSMVSNTSEE RANVIASALA KIPQKVLWRF DGNKPDTLGL NTRLYKWIPQ NDLLGHPKTR AFITHGGANG IYEAIYHGIP MVGVPLFADQ PDNIAHMKAK GAAVSLDFHT MSSTDLLNAL KTVINDPLYK ENAMKLSRIH HDQPVKPLDR AVFWIEFVMR HKGAKHLRVA A; Positive Samples: 22Rv1, B cells, HT-1080, Mouse liver, Mouse brain, Mouse kidney, Rat kidney; Cellular Location: Endoplasmic reticulum membrane, Microsome membrane, Single-pass membrane protein
Target Information
UGT2B4 belongs to the UDP-glycosyltransferase family. UDPGTs are of major importance in the conjugation and subsequent elimination of potentially toxic xenobiotics and endogenous compounds. This isozyme is active on polyhydroxylated estrogens (such as estriol, 4-hydroxyestrone and 2-hydroxyestriol) and xenobiotics (such as 4-methylumbelliferone, 1-naphthol, 4-nitrophenol, 2-aminophenol, 4-hydroxybiphenyl and menthol). It is capable of 6 alpha-hydroxyglucuronidation of hyodeoxycholic acid.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: HLUG25; hyodeoxycholic acid; Hyodeoxycholic acid-specific UDPGT; UDP glucuronosyltransferase 2 family, polypeptide B4; UDP-glucuronosyltransferase 2B4; UDP-glucuronyltransferase, family 2, beta-4; UDPGT 2B4; UDPGTh-1
Gene Aliases: HLUG25; UDPGT2B4; UDPGTh-1; UDPGTH1; UGT2B11; UGT2B4
UniProt ID: (Human) P06133
Entrez Gene ID: (Human) 7363
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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