Search Thermo Fisher Scientific
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Product Details
PA5-95854
| Applications | Tested Dilution | Publications |
|---|---|---|
Western Blot (WB) |
1:500-1:2,000 | - |
Immunocytochemistry (ICC/IF) |
1:50-1:100 | - |
| Product Specifications | |
|---|---|
Species Reactivity |
Human, Mouse, Rat |
Host/Isotype |
Rabbit / IgG |
Class |
Polyclonal |
Type |
Antibody |
Immunogen |
Recombinant fusion protein containing a sequence corresponding to amino acids 25-351 of human UGT2B7. |
Conjugate |
Unconjugated |
Form |
Liquid |
Concentration |
2.51 mg/mL |
Purification |
Affinity Chromatography |
Storage buffer |
PBS, pH 7.3, with 50% glycerol |
Contains |
0.01% thimerosal |
Storage conditions |
-20° C, Avoid Freeze/Thaw Cycles |
RRID |
AB_2807656 |
Product Specific Information
Immunogen sequence: KVLVWAAEYS HWMNIKTILD ELIQRGHEVT VLASSASILF DPNNSSALKI EIYPTSLTKT ELENFIMQQI KRWSDLPKDT FWLYFSQVQE IMSIFGDITR KFCKDVVSNK KFMKKVQESR FDVIFADAIF PCSELLAELF NIPFVYSLSF SPGYTFEKHS GGFIFPPSYV PVVMSELTDQ MTFMERVKNM IYVLYFDFWF EIFDMKKWDQ FYSEVLGRPT TLSETMGKAD VWLIRNSWNF QFPYPLLPNV DFVGGLHCKP AKPLPKEMED FVQSSGENGV VVFSLGSMVS NMTEERANVI ASALAQIPQK VLWRFDGNKP DTLGLNT; Positive Samples: HepG2, 293T; Cellular Location: Endoplasmic reticulum membrane, Microsome membrane, Single-pass membrane protein
Target Information
The UGTs serve a major role in the conjugation and subsequent elimination of potentially toxic xenobiotics and endogenous compounds. UGT2B7 has unique specificity for 3,4-catechol estrogens and estriol, suggesting that it may play an important role in regulating the level and activity of these potent estrogen metabolites. Its subcellular location is the microsome.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
References (0)
Have you cited this product in a publication?
Let us know so we can reference it here.
Bioinformatics
Protein Aliases: 3,4-catechol estrogen specific; 3,4-catechol estrogen-specific UDPGT; UDP glucuronosyltransferase 2 family, polypeptide B7; UDP glucuronosyltransferase 2B7; UDP-glucuronosyltransferase 2B7; UDP-glucuronosyltransferase 2B8; UDP-glucuronosyltransferase 2B9; UDP-glucuronyltransferase, family 2, beta-7; UDPGT 2B7; UDPGT 2B8; UDPGT 2B9; UDPGTh 2; UDPGTh-2; UGT2B-RH4
Gene Aliases: UDPGT 2B7; UDPGT 2B9; UDPGT2B7; UDPGTH2; UGT2B7; Ugt2b8; UGT2B9; UGTB2B9
UniProt ID: (Human) P16662, (Rat) Q62789
Entrez Gene ID: (Human) 7364, (Rat) 286989
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Learn more
We're here to help
Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.
Contact tech support