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Product Details
PA5-95854
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 25-351 of human UGT2B7 (NP_0010652)
Conjugate
Form
Liquid
Concentration
2.51 mg/mL
Purification
Affinity Chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2807656
Product Specific Information
Immunogen sequence: KVLVWAAEYS HWMNIKTILD ELIQRGHEVT VLASSASILF DPNNSSALKI EIYPTSLTKT ELENFIMQQI KRWSDLPKDT FWLYFSQVQE IMSIFGDITR KFCKDVVSNK KFMKKVQESR FDVIFADAIF PCSELLAELF NIPFVYSLSF SPGYTFEKHS GGFIFPPSYV PVVMSELTDQ MTFMERVKNM IYVLYFDFWF EIFDMKKWDQ FYSEVLGRPT TLSETMGKAD VWLIRNSWNF QFPYPLLPNV DFVGGLHCKP AKPLPKEMED FVQSSGENGV VVFSLGSMVS NMTEERANVI ASALAQIPQK VLWRFDGNKP DTLGLNT; Positive Samples: HepG2, 293T; Cellular Location: Endoplasmic reticulum membrane, Microsome membrane, Single-pass membrane protein
Target Information
The UGTs serve a major role in the conjugation and subsequent elimination of potentially toxic xenobiotics and endogenous compounds. UGT2B7 has unique specificity for 3,4-catechol estrogens and estriol, suggesting that it may play an important role in regulating the level and activity of these potent estrogen metabolites. Its subcellular location is the microsome.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: 3,4-catechol estrogen specific; 3,4-catechol estrogen-specific UDPGT; UDP glucuronosyltransferase 2 family, polypeptide B7; UDP glucuronosyltransferase 2B7; UDP-glucuronosyltransferase 2B7; UDP-glucuronosyltransferase 2B8; UDP-glucuronosyltransferase 2B9; UDP-glucuronyltransferase, family 2, beta-7; UDPGT; UDPGT 2B7; UDPGT 2B8; UDPGT 2B9; UDPGTh 2; UDPGTh-2; UGT2B-RH4
Gene Aliases: UDPGT 2B7; UDPGT 2B9; UDPGT2B7; UDPGTH2; UGT2B7; Ugt2b8; UGT2B9; UGTB2B9
UniProt ID: (Human) P16662, (Rat) Q62789
Entrez Gene ID: (Human) 7364, (Rat) 286989
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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