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Proteintech
UMPS Polyclonal Antibody
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Product Details
14830-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Published species
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
UMPS Fusion Protein Ag6620 (189-480 aa encoded by BC000364)
Conjugate
Form
Liquid
Concentration
0.15 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: VDAETVGRV KRFIQENVFV AANHNGSPLS IKEAPKELSF GARAELPRIH PVASKLLRLM QKKETNLCLS ADVSLARELL QLADALGPSI CMLKTHVDIL NDFTLDVMKE LITLAKCHEF LIFEDRKFAD IGNTVKKQYE GGIFKIASWA DLVNAHVVPG SGVVKGLQEV GLPLHRGCLL IAEMSSTGSL ATGDYTRAAV RMAEEHSEFV VGFISGSRVS MKPEFLHLTP GVQLEAGGDN LGQQYNSPQE VIGKRGSDII IVGRGIISAA DRLEAAEMYR KAAWEAYLSR LGV (189-480 aa encoded by BC000364)
Target Information
This gene encodes a uridine 5'-monophosphate synthase. The encoded protein is a bifunctional enzyme that catalyzes the final two steps of the de novo pyrimidine biosynthetic pathway. The first reaction is carried out by the N-terminal enzyme orotate phosphoribosyltransferase which converts orotic acid to orotidine-5'-monophosphate. The terminal reaction is carried out by the C-terminal enzyme OMP decarboxylase which converts orotidine-5'-monophosphate to uridine monophosphate. Defects in this gene are the cause of hereditary orotic aciduria. Alternate splicing results in multiple transcript variants.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: OMPdecase; OPRTase; orotate phosphoribosyltransferase; orotidine 5'-phosphate decarboxylase; UMP synthase; Uridine 5'-monophosphate synthase
Gene Aliases: 1700095D23Rik; AA408257; AL033308; BB164745; OK/SW-cl.21; OPRT; UMPS
UniProt ID: (Human) P11172, (Mouse) P13439
Entrez Gene ID: (Human) 7372, (Mouse) 22247
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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