Search
Invitrogen
UMPS Polyclonal Antibody
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promotions']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.viewpromo']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promocode']}}: {{promo.promoCode}} {{promo.promoTitle}} {{promo.promoDescription}}. {{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.learnmore']}}
Additional Information:
{{banner.description}}
Product Details
PA5-57559
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human UMPS. Recombinant protein control fragment (Product #RP-96305).
Conjugate
Form
Liquid
Concentration
0.2 mg/mL
Amount
20 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Immunogen sequence: GLKVTDAIVL LDREQGGKDK LQAHGIRLHS VCTLSKMLEI LEQQKKVDAE TVGRVKRFIQ ENVFVAANHN ASPLSIKEAP KELSFGARAE LPRIHPVA
Highest antigen sequence identity to the following orthologs: Mouse - 81%, Rat - 85%.
Target Information
This gene encodes a uridine 5'-monophosphate synthase. The encoded protein is a bifunctional enzyme that catalyzes the final two steps of the de novo pyrimidine biosynthetic pathway. The first reaction is carried out by the N-terminal enzyme orotate phosphoribosyltransferase which converts orotic acid to orotidine-5'-monophosphate. The terminal reaction is carried out by the C-terminal enzyme OMP decarboxylase which converts orotidine-5'-monophosphate to uridine monophosphate. Defects in this gene are the cause of hereditary orotic aciduria. Alternate splicing results in multiple transcript variants.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
References (0)
Have you cited this product in a publication?
Let us know so we can reference it here.
Bioinformatics
Protein Aliases: OMPdecase; OPRTase; orotate phosphoribosyltransferase; orotidine 5'-monophosphate decarboxylase (EC 4.1.1.23); orotidine 5'-phosphate decarboxylase; UMP synthase; UMPS; unnamed protein product; Uridine 5'-monophosphate synthase; uridine monophosphate synthase
Gene Aliases: 1700095D23Rik; AA408257; AL033308; BB164745; ODC; OK/SW-cl.21; OPRT; UMPS
UniProt ID: (Human) P11172, (Mouse) P13439
Entrez Gene ID: (Human) 7372, (Mouse) 22247, (Rat) 288051
'de novo' pyrimidine nucleobase biosynthetic process
pyrimidine nucleotide biosynthetic process
UMP biosynthetic process
UDP biosynthetic process
pyrimidine nucleobase biosynthetic process
'de novo' UMP biosynthetic process
metabolic process
nucleoside metabolic process
female pregnancy
lactation
cellular response to drug
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Learn more
We're here to help
Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.
Contact tech support