This antibody is predicted to react with Xenopus and zebrafish based on sequence homology.
Mouse Unc119b is related closely to Unc119, a homolog of C. elegans unc119 protein which was first discovered in C. elegans on the basis of a spontaneous mutation affecting locomotion, feeding behavior and chemosensation. Mouse Unc119b shares 90% sequence identity with human UNC119b protein. UNC119b is a myristoyl-binding protein that acts as a cargo adapter: specifically binds the myristoyl moiety of a subset of N-terminally myristoylated proteins and is required for their localization. Myristoyl-binding activity of UNC119b is required to localize NPHP3 to the primary cilium.
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Protein Aliases: POC7 centriolar protein homolog B; Protein unc-119 homolog B; unc-119 homolog B; unc119 homolog B
Gene Aliases: AA407659; AI414892; POC7B; UNC119B
Molecular Function: membrane traffic protein