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Product Details
29941-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
UNC5D fusion protein Ag31973
Conjugate
Form
Liquid
Concentration
0.8 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice
Product Specific Information
Immunogen sequence: ARGTDNGEAL PESIPSAPGT LPHFIEEPDD AYIIKSNPIA LRCKARPAMQ IFFKCNGEWV HQNEHVSEET LDESSGLKVR EVFINVTRQQ VEDFHGPEDY WCQCVAWSHL GTSKSRKASV
Target Information
UNC5D, also named as KIAA1777 and UNC5H4, belongs to the unc-5 family. It is a receptor for netrin. It may be involved in axon guidance by mediating axon repulsion of neuronal growth cones in the developing nervous system upon ligand binding. Axon repulsion in growth cones may be caused by its association with DCC that may trigger signaling for repulsion. It also acts as a dependence receptor required for apoptosis induction when not associated with netrin ligand.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: FLJ16019; KIAA1777Unc5h4; Netrin receptor UNC5D; netrin receptor Unc5h4; Protein unc-5 homolog 4; Protein unc-5 homolog D; unc-5 homolog 4; unc-5 homolog D; unc5 homolog 4
Gene Aliases: D930029E11Rik; KIAA1777; mKIAA1777; PRO34692; UNC5D; UNC5H4; UNQ6012/PRO34692
UniProt ID: (Human) Q6UXZ4, (Rat) F1LW30, (Mouse) Q8K1S2
Entrez Gene ID: (Human) 137970, (Rat) 306534, (Mouse) 210801
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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