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Proteintech
UPB1 Polyclonal Antibody
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Product Details
24603-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
UPB1 Fusion Protein Ag18960 (1-384 aa encoded by BC131703)
Conjugate
Form
Liquid
Concentration
0.25 mg/mL
Amount
37.5 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: MAGAEWKSL EECLEKHLPL PDLQEVKRVL YGKELRKLDL PREAFEAASR EDFELQGYAF EAAEEQLRRP RIVHVGLVQN RIPLPANAPV AEQVSALHRR IKAIVEVAAM CGVNIICFQE AWTMPFAFCT REKLPWTEFA ESAEDGPTTR FCQKLAKNHD MVVVSPILER DSEHGDVLWN TAVVISNSGA VLGKTRKNHI PRVGDFNEST YYMEGNLGHP VFQTQFGRIA VNICYGRHHP LNWLMYSING AEIIFNPSAT IGALSESLWP IEARNAAIAN HCFTCAINRV GTEHFPNEFT SGDGKKAHQD FGYFYGSSYV AAPDSSRTPG LSRSRDGLLV AKLDLNLCQQ VNDVWNFKMT GRYEMYAREL AEAVKSNYSP TIVKE (1-384 aa encoded by BC131703)
Target Information
UPB1 is a protein that belongs to the CN hydrolase family. Beta-ureidopropionase catalyzes the last step in the pyrimidine degradation pathway. The pyrimidine bases uracil and thymine are degraded via the consecutive action of dihydropyrimidine dehydrogenase (DHPDH), dihydropyrimidinase (DHP) and beta-ureidopropionase (UP) to beta-alanine and beta-aminoisobutyric acid, respectively. UP deficiencies are associated with N-carbamyl-beta-amino aciduria and may lead to abnormalities in neurological activity. This gene encodes a protein that belongs to the CN hydrolase family. Beta-ureidopropionase catalyzes the last step in the pyrimidine degradation pathway. The pyrimidine bases uracil and thymine are degraded via the consecutive action of dihydropyrimidine dehydrogenase (DHPDH), dihydropyrimidinase (DHP) and beta-ureidopropionase (UP) to beta-alanine and beta-aminoisobutyric acid, respectively. UP deficiencies are associated with N-carbamyl-beta-amino aciduria and may lead to abnormalities in neurological activity.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Beta-alanine synthase; Beta-ureidopropionase; BUP-1; Em:AP000355.2; N-carbamoyl-beta-alanine amidohydrolase; unnamed protein product; ureidopropionase, beta
Gene Aliases: AI195023; BUP1; UPB1
UniProt ID: (Human) Q9UBR1, (Mouse) Q8VC97
Entrez Gene ID: (Human) 51733, (Mouse) 103149
in utero embryonic development
liver development
CMP catabolic process
dCMP catabolic process
beta-alanine metabolic process
beta-alanine biosynthetic process
beta-alanine biosynthetic process via 3-ureidopropionate
small molecule metabolic process
UMP catabolic process
dUMP catabolic process
pyrimidine nucleoside catabolic process
protein homooligomerization
protein homotetramerization
nitrogen compound metabolic process
metabolic process
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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