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|Tested species reactivity||Human, Mouse|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Recombinant fragment corresponding to a region within amino acids 113 and 309 of Human UPRT|
|Purification||Antigen affinity chromatography|
|Storage buffer||0.1M tris glycine, pH 7, with 20% glycerol|
|Storage Conditions||-20° C, Avoid Freeze/Thaw Cycles|
|Tested Applications||Dilution *|
|Immunohistochemistry (Paraffin) (IHC (P))||1:100-1:1000|
|Western Blot (WB)||1:500-1:3000|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
PA5-31684 targets UPRT in IHC (P) and WB applications and shows reactivity with Human samples.
The PA5-31684 immunogen is recombinant fragment corresponding to a region within amino acids 113 and 309 of Human UPRT.
This gene encodes uracil phosphoribosyltransferase, which catalyzes the conversion of uracil and 5-phosphoribosyl-1-R-diphosphate to uridine monophosphate (UMP). This reaction is an important part of nucleotide metabolism, specifically the pyrimidine salvage pathway. The enzyme localizes to the nucleus and cytoplasm. The protein is a potential target for rational design of drugs to treat parasitic infections and cancer.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
FUR1; RP11-311P8.3; UMP pyrophosphorylase; UPP; UPRTase; uracil phosphoribosyltransferase (FUR1) homolog; uracil phosphoribosyltransferase homolog
FUR1; Gm774; UPP; UPRT