Proteintech

UQCRB Polyclonal Antibody

Product Image Gallery

UQCRB Antibody in Immunohistochemistry (Paraffin) (IHC (P)) — Immunohistochemistry of paraffin-embedded human kidney tissue slide using 10756-1-AP (UQCRB Antibody) at dilution of 1:50 (under 40x lens).

UQCRB Antibody in Western Blot (WB) — Human heart tissue were subjected to SDS PAGE followed by western blot with 10756-1-AP (UQCRB antibody) at dilution of 1:400 incubated at room temperature for 1.5 hours.

UQCRB Antibody in Immunoprecipitation (IP) — IP result of anti-UQCRB (IP:10756-1-AP, 3ug; Detection:10756-1-AP 1:600) with mouse heart tissue lysate 3200ug.

Product Details

10756-1-AP

Applications	Tested Dilution	Publications
Western Blot (WB)	1:200-1:1,000	View 6 publications 6 publications
Immunohistochemistry (Paraffin) (IHC (P))	1:20-1:200	-
Immunoprecipitation (IP)	0.5-4.0 µg	-

Product Specifications
Species Reactivity	Human, Mouse, Rat
Published species	Human, Mouse
Host/Isotype	Rabbit / IgG
Class	Polyclonal
Type	Antibody
Immunogen	UQCRB Fusion Protein Ag1127 (1-111 aa encoded by BC005230) View antigen
Conjugate	Unconjugated
Form	Liquid
Concentration	0.3 mg/mL
Purification	Antigen affinity chromatography
Storage buffer	PBS, pH 7.3, with 50% glycerol
Contains	0.1% sodium azide
Storage conditions	-20°C

Product Specific Information

Immunogen sequence: MAGKQAVSA SGKWLDGIRK WYYNAAGFNK LGLMRDDTIY EDEDVKEAIR RLPENLYNDR MFRIKRALDL NLKHQILPKE QWTKYEEENF YLEPYLKEVI RERKEREEWA KK (1-111 aa encoded by BC005230)

Target Information

UQCRB encodes a product that is a component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is part of the mitochondrial respiratory chain. This component is involved in redox-linked proton pumping.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Product References

TTC19 Plays a Husbandry Role on UQCRFS1 Turnover in the Biogenesis of Mitochondrial Respiratory Complex III.

Molecular cell

Bottani E,Cerutti R,Harbour ME,Ravaglia S,Dogan SA,Giordano C,Fearnley IM,D'Amati G,Viscomi C,Fernandez-Vizarra E,Zeviani M

Thu Jul 06 00:00:00 EDT 2017

CYC1 Predicts Poor Prognosis in Patients with Breast Cancer.

Disease markers

Han Y,Sun S,Zhao M,Zhang Z,Gong S,Gao P,Liu J,Zhou J,Ma D,Gao Q,Wu P

Mon Feb 20 00:00:00 EST 2017

Altered Mitochondria, Protein Synthesis Machinery, and Purine Metabolism Are Molecular Contributors to the Pathogenesis of Creutzfeldt-Jakob Disease.

Journal of neuropathology and experimental neurology

Ansoleaga B,Garcia-Esparcia P,Llorens F,Hernández-Ortega K,Carmona Tech M,Antonio Del Rio J,Zerr I,Ferrer I

Mon Aug 01 00:00:00 EDT 2016

Quantitative proteomics reveals oxygen-dependent changes in neuronal mitochondria affecting function and sensitivity to rotenone.

Journal of proteome research

Villeneuve L,Tiede LM,Morsey B,Fox HS

Fri Oct 04 00:00:00 EDT 2013

Mitochondrial complex III ROS regulate adipocyte differentiation.

Cell metabolism

Tormos KV,Anso E,Hamanaka RB,Eisenbart J,Joseph J,Kalyanaraman B,Chandel NS

Wed Oct 05 00:00:00 EDT 2011

Up-regulation of key microRNAs, and inverse down-regulation of their predicted oxidative phosphorylation target genes, during aging in mouse brain.

Neurobiology of aging

Li N,Bates DJ,An J,Terry DA,Wang E

Sun May 01 00:00:00 EDT 2011

Bioinformatics

Protein Aliases: Complex III subunit 7; Complex III subunit VII; Cytochrome b-c1 complex subunit 7; mitochondrial ubiquinone-binding protein; QP-C; ubiquinol-cytochrome c reductase binding protein-like; Ubiquinol-cytochrome c reductase complex 14 kDa protein; ubiquinol-cytochrome c reductase, complex III subunit VI

Gene Aliases: 2210415M14Rik; MC3DN3; QCR7; QP-C; QPC; UQBC; UQBP; UQCR6; UQCRB; Uqcrbl; UQPC

UniProt ID: (Human) P14927

Entrez Gene ID: (Human) 7381, (Mouse) 67530, (Rat) 362897

Molecular Function: oxidoreductase reductase metabolite interconversion enzyme