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URAT1 Polyclonal Antibody

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Antibody Testing Data (6)

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URAT1 Antibody (14937-1-AP) in WB

Mouse kidney tissue were subjected to SDS PAGE followed by western blot with (Product # 14937-1-AP) Urat1 antibody at dilution of 1:1,500 incubated at room temperature for 1.5 hours.

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Product Details

14937-1-AP

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:1,000

View 51 publications 51 publications

Immunohistochemistry (IHC)

View 4 publications 4 publications

Immunocytochemistry (ICC/IF)

View 1 publication 1 publication

Not applicable (N/A)

View 1 publication 1 publication

Product Specifications

Species Reactivity

Human, Mouse, Pig, Rat

Published species

Human, Mouse, Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

URAT1 Fusion Protein Ag6770 (4-351 aa encoded by BC053348)

View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.57 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Wet ice (domestic); Dry ice (international)

Product Specific Information

This antibody recognizes the native and glycosylated URAT1 between 65 and 70 kDa as well as the truncated 40 kDa protein.

Immunogen sequence: SELLDLVGG LGRFQVLQTM ALMVSIMWLC TQSMLENFSA AVPSHRCWAP LLDNSTAQAS ILGSLSPEAL LAISIPPGPN QRPHQCRRFR QPQWQLLDPN ATATSWSEAD TEPCVDGWVY DRSIFTSTIV AKWNLVCDSH ALKPMAQSIY LAGILVGAAA CGPASDRFGR RLVLTWSYLQ MAVMGTAAAF APAFPVYCLF RFLLAFAVAG VMMNTGTLLM EWTAARARPL VMTLNSLGFS FGHGLTAAVA YGVRDWTLLQ LVVSVPFFLC FLYSWWLAES ARWLLTTGRL DWGLQELWRV AAINGKGAVQ DTLTPEVLLS AMREELSMGQ PPASLGTLLR MPGLRFRTC (4-351 aa encoded by BC053348 )

Target Information

SLC22A12 is required for efficient urate re-absorption in the kidney. SLC22A12 regulates blood urate levels. SLC22A12 mediates saturable urate uptake by facilitating the exchange of urate against organic anions.The protein encoded by this gene is a urate transporter and urate-anion exchanger which regulates the level of urate in the blood. This protein is an integral membrane protein primarily found in kidney. Two transcript variants encoding different isoforms have been found for this gene.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Product References

Hypouricemic and nephroprotective effects of palmatine from Cortex Phellodendri Amurensis: A uric acid modulator targeting Keap1-Nrf2/NLRP3 axis.

Journal of ethnopharmacology

Ai G,Huang R,Xie J,Zhong L,Wu X,Qin Z,Su Z,Chen J,Yang X,Dou Y

Mon Jan 30 00:00:00 EST 2023

Sanghuangporus vaninii ethanol extract alleviates hyperuricemic renal injury by regulating the uric acid transporters and inhibiting HK-2 apoptosis.

Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie

Hua L,Zhang S,Yang J,Zhou X,Shi S

Tue Aug 01 00:00:00 EDT 2023

Multi-omics analysis reveals therapeutic effects of Bacillus subtilis-fermented Astragalus membranaceus in hyperuricemia via modulation of gut microbiota.

Food chemistry

Wang R,Lin F,Ye C,Aihemaitijiang S,Halimulati M,Huang X,Jiang Z,Li L,Zhang Z

Sun Jan 15 00:00:00 EST 2023

Simiao San alleviates hyperuricemia and kidney inflammation by inhibiting NLRP3 inflammasome and JAK2/STAT3 signaling in hyperuricemia mice.

Journal of ethnopharmacology

Zhang Y,Wang S,Dai X,Liu T,Liu Y,Shi H,Yin J,Xu T,Zhang Y,Zhao D,Sukhorukov V,Orekhov AN,Gao S,Wang L,Zhang D

Thu Aug 10 00:00:00 EDT 2023

Amelioration effects of α-viniferin on hyperuricemia and hyperuricemia-induced kidney injury in mice.

Phytomedicine : international journal of phytotherapy and phytopharmacology

Guo XL,Gao YY,Yang YX,Zhu QF,Guan HY,He X,Zhang CL,Wang Y,Xu GB,Zou SH,Wei MC,Zhang J,Zhang JJ,Liao SG

Tue Jul 25 00:00:00 EDT 2023

Ferulic acid supplementation alleviates hyperuricemia in high-fructose/fat diet-fed rats via promoting uric acid excretion and mediating the gut microbiota.

Food & function

Zhang N,Zhou J,Zhao L,Zhao Z,Wang S,Zhang L,Zhou F

Mon Feb 06 00:00:00 EST 2023

Identification and Anti-Hyperuricemic Activity of Xanthine Oxidase Inhibitory Peptides from Pacific White Shrimp and Swimming Crab Based on Molecular Docking Screening.

Journal of agricultural and food chemistry

Mao Z,Jiang H,Mao X

Wed Jan 25 00:00:00 EST 2023

Anti-Hyperuricemic Effect of Anserine Based on the Gut-Kidney Axis: Integrated Analysis of Metagenomics and Metabolomics.

Nutrients

Halimulati M,Wang R,Aihemaitijiang S,Huang X,Ye C,Zhang Z,Li L,Zhu W,Zhang Z,He L

Wed Feb 15 00:00:00 EST 2023

Naringenin Ameliorates Hyperuricemia by Regulating Renal Uric Acid Excretion via the PI3K/AKT Signaling Pathway and Renal Inflammation through the NF-κB Signaling Pathway.

Journal of agricultural and food chemistry

Yang B,Xin M,Liang S,Huang Y,Li J,Wang C,Liu C,Song X,Sun J,Sun W

Wed Jan 25 00:00:00 EST 2023

Hyperuricemia exacerbates abdominal aortic aneurysm formation through the URAT1/ERK/MMP-9 signaling pathway.

BMC cardiovascular disorders

Wang JC,Tsai SH,Tsai HY,Lin SJ,Huang PH

Mon Jan 30 00:00:00 EST 2023

Oxyberberrubine, a novel liver microsomes-mediated secondary metabolite of berberine, alleviates hyperuricemic nephropathy in mice.

Phytomedicine : international journal of phytotherapy and phytopharmacology

Zhong L,Lin Y,Gong S,Wu X,Liu Y,Chen J,Li Y,Yan F,Su Z,Xie Q

Sun Jan 01 00:00:00 EST 2023

Hypouricemic effect of 2,4-dihydroxybenzoic acid methyl ester in hyperuricemic mice through inhibiting XOD and down-regulating URAT1.

Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie

Yong T,Liang D,Xiao C,Huang L,Chen S,Xie Y,Gao X,Wu Q,Hu H,Li X,Liu Y,Cai M

Thu Sep 01 00:00:00 EDT 2022

Fufang Zhenzhu Tiaozhi capsule ameliorates hyperuricemic nephropathy by inhibition of PI3K/AKT/NF-κB pathway.

Journal of ethnopharmacology

Li MH,Guan J,Chen Z,Mo JX,Wu KR,Hu XG,Lan T,Guo J

Tue Nov 15 00:00:00 EST 2022

Apigenin Ameliorates Hyperuricemia and Renal Injury through Regulation of Uric Acid Metabolism and JAK2/STAT3 Signaling Pathway.

Pharmaceuticals (Basel, Switzerland)

Liu T,Gao H,Zhang Y,Wang S,Lu M,Dai X,Liu Y,Shi H,Xu T,Yin J,Gao S,Wang L,Zhang D

Mon Nov 21 00:00:00 EST 2022

Live and pasteurized Akkermansia muciniphila attenuate hyperuricemia in mice through modulating uric acid metabolism, inflammation, and gut microbiota.

Food & function

Zhang L,Liu J,Jin T,Qin N,Ren X,Xia X

Mon Nov 28 00:00:00 EST 2022

URAT1-selective inhibition ameliorates insulin resistance by attenuating diet-induced hepatic steatosis and brown adipose tissue whitening in mice.

Molecular metabolism

Tanaka Y,Nagoshi T,Takahashi H,Oi Y,Yoshii A,Kimura H,Ito K,Kashiwagi Y,Tanaka TD,Yoshimura M

Sat Jan 01 00:00:00 EST 2022

Effects of polysaccharides-riched Prunus mume fruit juice concentrate on uric acid excretion and gut microbiota in mice with adenine-induced chronic kidney disease.

Current research in food science

Huang Y,Wu CX,Guo L,Zhang XX,Xia DZ

Fri Nov 18 00:00:00 EST 2022

Berberine Attenuates Hyperuricemia by Regulating Urate Transporters and Gut Microbiota.

The American journal of Chinese medicine

Shan B,Wu M,Chen T,Tang W,Li P,Chen J

Fri Nov 25 00:00:00 EST 2022

Effects of black tea and black brick tea with fungal growth on lowering uric acid levels in hyperuricemic mice.

Journal of food biochemistry

Yuan D,Lin L,Peng Y,Zhou Y,Li L,Xiao W,Gong Z

Fri Jul 01 00:00:00 EDT 2022

Resveratrol affects the expression of uric acid transporter by improving inflammation.

Molecular medicine reports

Zhang X,Nie Q,Zhang Z,Zhao J,Zhang F,Wang C,Wang X,Song G

Sun Aug 01 00:00:00 EDT 2021

The Active Components of Sunflower (Helianthus annuus L.) Calathide and the Effects on Urate Nephropathy Based on COX-2/PGE2 Signaling Pathway and the Urate Transporter URAT1, ABCG2, and GLUT9.

Frontiers in nutrition

Dai H,Lv S,Qiao Z,Wang K,Zhou X,Bao C,Zhang S,Fu X,Li W

Fri Jan 28 00:00:00 EST 2022

Low Expression Levels of SLC22A12 Indicates a Poor Prognosis and Progresses Clear Cell Renal Cell Carcinoma.

Frontiers in oncology

Xu J,Liu Y,Liu J,Shou Y,Xiong Z,Xiong H,Xu T,Wang Q,Liu D,Liang H,Yang H,Yang X,Zhang X

Tue Jul 13 00:00:00 EDT 2021

Antihyperuricemia and antigouty arthritis effects of Persicaria capitata herba in mice.

Phytomedicine : international journal of phytotherapy and phytopharmacology

Zhang CL,Zhang JJ,Zhu QF,Guan HY,Yang YX,He X,Fu Y,Chen TX,Dong L,Yang XS,Tang KF,Xu GB,Liao SG

Wed Dec 01 00:00:00 EST 2021

Anti-Hyperuricemic and Nephroprotective Effects of Dihydroberberine in Potassium Oxonate- and Hypoxanthine-Induced Hyperuricemic Mice.

Frontiers in pharmacology

Xu L,Lin G,Yu Q,Li Q,Mai L,Cheng J,Xie J,Liu Y,Su Z,Li Y

Sat May 08 00:00:00 EDT 2021

Effect of Berberine on Hyperuricemia and Kidney Injury: A Network Pharmacology Analysis and Experimental Validation in a Mouse Model.

Drug design, development and therapy

Li Q,Huang Z,Liu D,Zheng J,Xie J,Chen J,Zeng H,Su Z,Li Y

Mon Jan 10 00:00:00 EST 2022

Effect of Berberine on Hyperuricemia and Kidney Injury: A Network Pharmacology Analysis and Experimental Validation in a Mouse Model.

Drug design, development and therapy

Li Q,Huang Z,Liu D,Zheng J,Xie J,Chen J,Zeng H,Su Z,Li Y

Mon Jan 10 00:00:00 EST 2022

Active components from Lagotis brachystachya maintain uric acid homeostasis by inhibiting renal TLR4-NLRP3 signaling in hyperuricemic mice.

Inflammopharmacology

Zhu JX,Yang HY,Hu WQ,Cheng J,Liu Y,Yi LT,Cheng HY

Sun Aug 01 00:00:00 EDT 2021

Anti-Inflammatory and Anti-Hyperuricemic Effects of Chrysin on a High Fructose Corn Syrup-Induced Hyperuricemia Rat Model via the Amelioration of Urate Transporters and Inhibition of NLRP3 Inflammasome Signaling Pathway.

Antioxidants (Basel, Switzerland)

Chang YH,Chiang YF,Chen HY,Huang YJ,Wang KL,Hong YH,Ali M,Shieh TM,Hsia SM

Tue Apr 06 00:00:00 EDT 2021

Withaferin A protects against hyperuricemia induced kidney injury and its possible mechanisms.

Bioengineered

Zhao X,Wang J,Tang L,Li P,Ru J,Bai Y

Wed Dec 01 00:00:00 EST 2021

Anti-hyperuricemic and nephroprotective effects of whey protein hydrolysate in potassium oxonate induced hyperuricemic rats.

Journal of the science of food and agriculture

Qi X,Chen H,Guan K,Wang R,Ma Y

Wed Sep 01 00:00:00 EDT 2021

Olsalazine Sodium Increases Renal Urate Excretion by Modulating Urate Transporters in Hyperuricemic Animals.

Biological & pharmaceutical bulletin

Niu Y,Yang P,Li H,Li Q,Lin H,Gao L,Li L

Sun Nov 01 00:00:00 EDT 2020

Multiple-Purpose Connectivity Map Analysis Reveals the Benefits of Esculetin to Hyperuricemia and Renal Fibrosis.

International journal of molecular sciences

Wang Y,Kong W,Wang L,Zhang T,Huang B,Meng J,Yang B,Xie Z,Zhou H

Sun Oct 18 00:00:00 EDT 2020

Total glucosides of herbaceous peony (Paeonia lactiflora Pall.) flower attenuate adenine- and ethambutol-induced hyperuricaemia in rats.

Journal of ethnopharmacology

Kang L,Miao JX,Cao LH,Miao YY,Miao MS,Liu HJ,Xiang LL,Song YG

Wed Oct 28 00:00:00 EDT 2020

Anti-hyperuricemic potential of stevia (Stevia rebaudiana Bertoni) residue extract in hyperuricemic mice.

Food & function

Mehmood A,Zhao L,Ishaq M,Xin W,Zhao L,Wang C,Hossen I,Zhang H,Lian Y,Xu M

Wed Jul 22 00:00:00 EDT 2020

Discovery of a novel rice-derived peptide with significant anti-gout potency.

Food & function

Liu N,Meng B,Zeng L,Yin S,Hu Y,Li S,Fu Y,Zhang X,Xie C,Shu L,Yang M,Wang Y,Yang X

Tue Dec 01 00:00:00 EST 2020

RDP3, A Novel Antigout Peptide Derived from Water Extract of Rice.

Journal of agricultural and food chemistry

Liu N,Wang Y,Zeng L,Yin S,Hu Y,Li S,Fu Y,Zhang X,Xie C,Shu L,Li Y,Sun H,Yang M,Sun J,Yang X

Wed Jul 08 00:00:00 EDT 2020

The mechanism of Arhalofenate in alleviating hyperuricemia-Activating PPARγ thereby reducing caspase-1 activity.

Drug development research

Wang G,Zuo T,Li R

Sun Nov 01 00:00:00 EDT 2020

Antihyperuricemic and nephroprotective effects of extracts from Orthosiphon stamineus in hyperuricemic mice.

The Journal of pharmacy and pharmacology

Xu WH,Wang HT,Sun Y,Xue ZC,Liang ML,Su WK

Wed Apr 01 00:00:00 EDT 2020

Dual actions of norathyriol as a new candidate hypouricaemic agent: uricosuric effects and xanthine oxidase inhibition.

European journal of pharmacology

Lin H,Tu C,Niu Y,Li F,Yuan L,Li N,Xu A,Gao L,Li L

Sat Jun 15 00:00:00 EDT 2019

Preventive Effects of Fucoidan and Fucoxanthin on Hyperuricemic Rats Induced by Potassium Oxonate.

Marine drugs

Chau YT,Chen HY,Lin PH,Hsia SM

Mon Jun 10 00:00:00 EDT 2019

Effect of Eurycoma longifolia Stem Extract on Uric Acid Excretion in Hyperuricemia Mice.

Frontiers in pharmacology

Bao R,Liu M,Wang D,Wen S,Yu H,Zhong Y,Li Z,Zhang Y,Wang T

Wed Sep 30 00:00:00 EDT 2020

Effects of Alismatis Rhizoma and Rhizoma Smilacis Glabrae Decoction on Hyperuricemia in Rats.

Evidence-based complementary and alternative medicine : eCAM

Cheng S,Sun H,Li X,Yan J,Peng Z,You Y,Zhang L,Chen J

Thu Oct 01 00:00:00 EDT 2020

Conjugated Linoleic Acid Ameliorates High Fructose-Induced Hyperuricemia and Renal Inflammation in Rats via NLRP3 Inflammasome and TLR4 Signaling Pathway.

Molecular nutrition & food research

Tan J,Wan L,Chen X,Li X,Hao X,Li X,Li J,Ding H

Sat Jun 01 00:00:00 EDT 2019

MiR-143-3p directly targets GLUT9 to reduce uric acid reabsorption and inflammatory response of renal tubular epithelial cells.

Biochemical and biophysical research communications

Zhou Z,Dong Y,Zhou H,Liu J,Zhao W

Tue Sep 24 00:00:00 EDT 2019

Urate transport capacity of glucose transporter 9 and urate transporter 1 in cartilage chondrocytes.

Molecular medicine reports

Zhang B,Duan M,Long B,Zhang B,Wang D,Zhang Y,Chen J,Huang X,Jiao Y,Zhu L,Zeng X

Thu Aug 01 00:00:00 EDT 2019

Urate transport capacity of glucose transporter 9 and urate transporter 1 in cartilage chondrocytes.

Molecular medicine reports

Zhang B,Duan M,Long B,Zhang B,Wang D,Zhang Y,Chen J,Huang X,Jiao Y,Zhu L,Zeng X

Thu Aug 01 00:00:00 EDT 2019

Urate transport capacity of glucose transporter 9 and urate transporter 1 in cartilage chondrocytes.

Molecular medicine reports

Zhang B,Duan M,Long B,Zhang B,Wang D,Zhang Y,Chen J,Huang X,Jiao Y,Zhu L,Zeng X

Thu Aug 01 00:00:00 EDT 2019

Research on the pharmacodynamics and mechanism of Fraxini Cortex on hyperuricemia based on the regulation of URAT1 and GLUT9.

Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie

Zhou Y,Zhang X,Li C,Yuan X,Han L,Li Z,Tan X,Song J,Wang G,Jia X,Feng L,Qiao X,Liu J

Mon Oct 01 00:00:00 EDT 2018

Research on the pharmacodynamics and mechanism of Fraxini Cortex on hyperuricemia based on the regulation of URAT1 and GLUT9.

Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie

Zhou Y,Zhang X,Li C,Yuan X,Han L,Li Z,Tan X,Song J,Wang G,Jia X,Feng L,Qiao X,Liu J

Mon Oct 01 00:00:00 EDT 2018

Hypouricemic Effects of Armillaria mellea on Hyperuricemic Mice Regulated through OAT1 and CNT2.

The American journal of Chinese medicine

Yong T,Chen S,Xie Y,Chen D,Su J,Shuai O,Hu H,Zuo D,Liang D

Mon Jul 23 00:00:00 EDT 2018

Hypouricemic Effects of Armillaria mellea on Hyperuricemic Mice Regulated through OAT1 and CNT2.

The American journal of Chinese medicine

Yong T,Chen S,Xie Y,Chen D,Su J,Shuai O,Hu H,Zuo D,Liang D

Mon Jul 23 00:00:00 EDT 2018

Cordycepin, a Characteristic Bioactive Constituent in Cordyceps militaris, Ameliorates Hyperuricemia through URAT1 in Hyperuricemic Mice.

Frontiers in microbiology

Yong T,Chen S,Xie Y,Chen D,Su J,Shuai O,Jiao C,Zuo D

Thu Oct 01 00:00:00 EDT 2020

Cordycepin, a Characteristic Bioactive Constituent in Cordyceps militaris, Ameliorates Hyperuricemia through URAT1 in Hyperuricemic Mice.

Frontiers in microbiology

Yong T,Chen S,Xie Y,Chen D,Su J,Shuai O,Jiao C,Zuo D

Thu Oct 01 00:00:00 EDT 2020

Hypouricemic Effects of Extracts From Agrocybe aegerita on Hyperuricemia Mice and Virtual Prediction of Bioactives by Molecular Docking.

Frontiers in pharmacology

Yong T,Chen S,Xie Y,Shuai O,Li X,Chen D,Su J,Jiao C,Liang Y

Thu Oct 01 00:00:00 EDT 2020

Hypouricemic Effects of Extracts From Agrocybe aegerita on Hyperuricemia Mice and Virtual Prediction of Bioactives by Molecular Docking.

Frontiers in pharmacology

Yong T,Chen S,Xie Y,Shuai O,Li X,Chen D,Su J,Jiao C,Liang Y

Thu Oct 01 00:00:00 EDT 2020

Urate inhibits microglia activation to protect neurons in an LPS-induced model of Parkinson's disease.

Journal of neuroinflammation

Bao LH,Zhang YN,Zhang JN,Gu L,Yang HM,Huang YY,Xia N,Zhang H

Wed May 02 00:00:00 EDT 2018

Urate inhibits microglia activation to protect neurons in an LPS-induced model of Parkinson's disease.

Journal of neuroinflammation

Bao LH,Zhang YN,Zhang JN,Gu L,Yang HM,Huang YY,Xia N,Zhang H

Wed May 02 00:00:00 EDT 2018

Effects of Gnaphalium affine D. Don on hyperuricemia and acute gouty arthritis.

Journal of ethnopharmacology

Zhang HJ,Li LN,Zhou J,Yang QQ,Liu PG,Xu P,Liang WQ,Cheng L,Zhang YQ,Pu JB,Hu YJ

Fri May 05 00:00:00 EDT 2017

Effects of Gnaphalium affine D. Don on hyperuricemia and acute gouty arthritis.

Journal of ethnopharmacology

Zhang HJ,Li LN,Zhou J,Yang QQ,Liu PG,Xu P,Liang WQ,Cheng L,Zhang YQ,Pu JB,Hu YJ

Fri May 05 00:00:00 EDT 2017

Taurine decreased uric acid levels in hyperuricemic rats and alleviated kidney injury.

Biochemical and biophysical research communications

Feng Y,Sun F,Gao Y,Yang J,Wu G,Lin S,Hu J

Sat Jul 29 00:00:00 EDT 2017

Taurine decreased uric acid levels in hyperuricemic rats and alleviated kidney injury.

Biochemical and biophysical research communications

Feng Y,Sun F,Gao Y,Yang J,Wu G,Lin S,Hu J

Sat Jul 29 00:00:00 EDT 2017

Hypouricemic Effects of Ganoderma applanatum in Hyperuricemia Mice through OAT1 and GLUT9.

Frontiers in pharmacology

Yong T,Chen S,Xie Y,Chen D,Su J,Shuai O,Jiao C,Zuo D

Fri Mar 18 00:00:00 EDT 2022

Hypouricemic Effects of Ganoderma applanatum in Hyperuricemia Mice through OAT1 and GLUT9.

Frontiers in pharmacology

Yong T,Chen S,Xie Y,Chen D,Su J,Shuai O,Jiao C,Zuo D

Fri Mar 18 00:00:00 EDT 2022

Caffeoylquinic acid derivatives rich extract from Gnaphalium pensylvanicum willd. Ameliorates hyperuricemia and acute gouty arthritis in animal model.

BMC complementary and alternative medicine

Jiang Y,Lin Y,Hu YJ,Song XJ,Pan HH,Zhang HJ

Sat Jun 17 00:00:00 EDT 2017

Caffeoylquinic acid derivatives rich extract from Gnaphalium pensylvanicum willd. Ameliorates hyperuricemia and acute gouty arthritis in animal model.

BMC complementary and alternative medicine

Jiang Y,Lin Y,Hu YJ,Song XJ,Pan HH,Zhang HJ

Sat Jun 17 00:00:00 EDT 2017

Uric acid crystal could inhibit Numb-induced URAT1 lysosome degradation in uric acid nephropathy.

Journal of physiology and biochemistry

Wu X,Zhang J,Liu T,Yan M,Liu H,Xie H,Zhang S,Sun B,Ke B,Zhou H

Mon Jun 01 00:00:00 EDT 2015

Uric acid crystal could inhibit Numb-induced URAT1 lysosome degradation in uric acid nephropathy.

Journal of physiology and biochemistry

Wu X,Zhang J,Liu T,Yan M,Liu H,Xie H,Zhang S,Sun B,Ke B,Zhou H

Mon Jun 01 00:00:00 EDT 2015

Uric acid crystal could inhibit Numb-induced URAT1 lysosome degradation in uric acid nephropathy.

Journal of physiology and biochemistry

Wu X,Zhang J,Liu T,Yan M,Liu H,Xie H,Zhang S,Sun B,Ke B,Zhou H

Mon Jun 01 00:00:00 EDT 2015

Bioinformatics

Protein Aliases: Organic anion transporter 4-like protein; Renal-specific transporter; RST; solute carrier family 22 (organic anion/cation transporter), member 12; solute carrier family 22 (organic anion/urate transporter), member 12; solute carrier family 22 (organic cation transporter)-like 2; Solute carrier family 22 member 12; URAT1; Urate anion exchanger 1; urate transporter 1; Urate:anion antiporter SLC22A12

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Gene Aliases: AI987855; OAT4L; OATL4; RST; SLC22A12; Slc22al2; UNQ6453/PRO34004; URAT1

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UniProt ID: (Human) Q96S37, (Rat) Q3ZAV1, (Mouse) Q8CFZ5

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Entrez Gene ID: (Pig) 100520540, (Human) 116085, (Rat) 365398, (Mouse) 20521

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Function(s)

inorganic anion exchanger activity urate transmembrane transporter activity sodium-independent organic anion transmembrane transporter activity PDZ domain binding molecular_function protein binding transmembrane transporter activity secondary carrier transporter

Process(es)

inorganic anion transport urate transport cellular homeostasis response to drug sodium-independent organic anion transport urate metabolic process organic acid transmembrane transport biological_process organic acid transport transmembrane transport transport ion transport

Performance Guarantee

If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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URAT1 Polyclonal Antibody

URAT1 Antibody (14937-1-AP) in WB

Product Details

14937-1-AP

Western Blot (WB)

Immunohistochemistry (IHC)

Immunocytochemistry (ICC/IF)

Not applicable (N/A)

Species Reactivity

Published species

Host/Isotype

Class

Type

Immunogen

Conjugate

Form

Concentration

Purification

Storage buffer

Contains

Storage conditions

Shipping conditions

Product Specific Information

Target Information

Bioinformatics

Performance Guarantee

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