Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
Immunogen sequence: HELDTTGEC LVDLGSDQTS CHNPFNGGYY PVQLSFTEAQ SLMASNPAVF KDLVQESLRR QVSAINRLAE EKFFFWDYGN AFLLEAQRAG ADVEKKGAGR TEFRYPSYVQ HIMGDIFSQG FGPFRWVCTS GDPQDLAVTD ELATSVLEEA IADGVKVSVK LQYMDNIRWI REAARHRLVV GSQARILYSD QKGRVAIAVA INQAIACRRI KAPVVLSRDH HDVSGTDSPF RETSNIYDGS AFCADMAVQN FVGDACRGAT WVALHNGGGV GWGEVINGGF GLVLDGTPEA EGRARLMLSW DVSNGVARRC WSGNQKAYEI ICQTMQENST LVVTLPHKVE DERVLQQALQ L (327-676 aa encoded by BC115405)
This gene encodes an enzyme involved in histidine catabolism, metabolizing urocanic acid to formiminoglutamic acid. The gene product is known to protect the skin from ultra violet rays and is contained in human sweat. Deficiency of this gene product in the liver is an apparent cause of mental retardation. Multiple transcript variants encoding different isoforms have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Imidazolonepropionate hydrolase; Urocanase; urocanase 1; urocanase domain containing 1; Urocanate hydratase
Gene Aliases: AI265605; BC022133; HMFN0320; UROC1; UROCD
UniProt ID: (Human) Q96N76, (Mouse) Q8VC12
Entrez Gene ID: (Human) 131669, (Mouse) 243537
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